Detailed information of TA system TA046802

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1909644..1909824
• Replicon: chromosome
• Accession: NZ_CP007659
• Organism: Staphylococcus aureus strain H-EMRSA-15

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ER16_RS15305
• Protein ID: WP_001801861.1
• Coordinates: 1909644..1909739 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1909767..1909824 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ER16_RS09340	1904931..1905698	-	768	WP_001095317.1	IS21-like element helper ATPase IstB	-
ER16_RS09345	1905710..1906945	-	1236	WP_001215400.1	IS21 family transposase	-
ER16_RS09350	1907303..1907872	-	570	WP_000864144.1	ImmA/IrrE family metallo-endopeptidase	-
ER16_RS09360	1908245..1908421	-	177	WP_000375476.1	hypothetical protein	-
ER16_RS09365	1908432..1908815	-	384	WP_000070809.1	hypothetical protein	-
ER16_RS14880	1909395..1909499	-	105	WP_001670380.1	transposase	-
ER16_RS15305	1909644..1909739	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1909767..1909824	-	58	-	-	Antitoxin
ER16_RS09375	1909862..1909963	+	102	WP_001791232.1	hypothetical protein	-
ER16_RS15310	1909941..1910113	-	173	Protein_1802	transposase	-
ER16_RS09380	1910307..1910684	-	378	WP_001036002.1	DUF1433 domain-containing protein	-
ER16_RS09385	1910890..1911330	-	441	WP_000759947.1	DUF1433 domain-containing protein	-
ER16_RS09390	1911375..1912988	+	1614	WP_000926708.1	lipase	-
ER16_RS09395	1913003..1913302	+	300	WP_000095392.1	WXG100 family type VII secretion target	-
ER16_RS09400	1913619..1914800	-	1182	WP_000162901.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	1900664..1926054	25390

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T46802 WP_001801861.1 NZ_CP007659:1909644-1909739 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T46802 NZ_CP007659:1909644-1909739 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT46802 NZ_CP007659:c1909824-1909767 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin