Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2224327..2224544 Replicon chromosome
Accession NZ_CP007657
Organism Staphylococcus aureus strain V2200

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EP20_RS11345 Protein ID WP_001802298.1
Coordinates 2224440..2224544 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2224327..2224382 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EP20_RS11325 2220464..2221129 - 666 WP_001024094.1 SDR family oxidoreductase -
EP20_RS11330 2221281..2221601 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EP20_RS11335 2221603..2222583 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
EP20_RS11340 2222849..2223940 + 1092 WP_000495671.1 lytic regulatory protein -
- 2224327..2224382 + 56 - - Antitoxin
EP20_RS11345 2224440..2224544 - 105 WP_001802298.1 hypothetical protein Toxin
EP20_RS15540 2224705..2225188 - 484 Protein_2143 recombinase family protein -
EP20_RS11355 2225231..2226367 - 1137 WP_000115564.1 SAP domain-containing protein -
EP20_RS11360 2226656..2226748 + 93 WP_001790138.1 hypothetical protein -
EP20_RS11365 2227453..2228310 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
EP20_RS11370 2228378..2229160 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T46790 WP_001802298.1 NZ_CP007657:c2224544-2224440 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T46790 NZ_CP007657:c2224544-2224440 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT46790 NZ_CP007657:2224327-2224382 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References