46720

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1141955..1142117 Replicon chromosome
Accession NZ_CP007601
Organism Staphylococcus capitis subsp. capitis strain AYP1020

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A507SQ11
Locus tag ayp1020_RS05335 Protein ID WP_030063529.1
Coordinates 1142013..1142117 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1141955..1141985 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ayp1020_RS05310 1138146..1138886 - 741 WP_047796431.1 ABC transporter ATP-binding protein -
ayp1020_RS05315 1139019..1139444 + 426 WP_047796432.1 HIT family protein -
ayp1020_RS05320 1139522..1139893 + 372 WP_002434824.1 YtxH domain-containing protein -
ayp1020_RS05325 1140085..1140654 + 570 WP_002434864.1 DUF3267 domain-containing protein -
ayp1020_RS05330 1140857..1141858 + 1002 WP_023350053.1 peptidylprolyl isomerase -
- 1141955..1141985 - 31 - - Antitoxin
ayp1020_RS05335 1142013..1142117 - 105 WP_030063529.1 type I toxin-antitoxin system Fst family toxin Toxin
ayp1020_RS05340 1142308..1143249 - 942 WP_002434737.1 3'-5' exoribonuclease YhaM -
ayp1020_RS05345 1143246..1146185 - 2940 WP_047796433.1 AAA family ATPase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3963.74 Da        Isoelectric Point: 10.7588

>T46720 WP_030063529.1 NZ_CP007601:c1142117-1142013 [Staphylococcus capitis subsp. capitis]
MLFDIFVHIMATATSGCIVALFAHWLRTRNDKRK

Download         Length: 105 bp

>T46720 NZ_CP007601:c1142117-1142013 [Staphylococcus capitis subsp. capitis]
ATGTTATTTGATATCTTTGTACACATCATGGCCACGGCAACCAGTGGTTGTATCGTTGCTTTATTCGCGCATTGGCTACG
CACTCGCAACGATAAACGTAAATAG

Antitoxin


Download         Length: 31 bp

>AT46720 NZ_CP007601:c1141985-1141955 [Staphylococcus capitis subsp. capitis]
AAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A507SQ11


Antitoxin

Download structure file

References