Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1554354..1554859 Replicon chromosome
Accession NZ_CP007595
Organism Arthrobacter sp. PAMC 25486

Toxin (Protein)


Gene name yoeB Uniprot ID A0A0A1D0B0
Locus tag art_RS07055 Protein ID WP_038463460.1
Coordinates 1554602..1554859 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0A1CV86
Locus tag art_RS07050 Protein ID WP_038463458.1
Coordinates 1554354..1554605 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
art_RS07045 1550157..1554215 + 4059 WP_038463456.1 ATP-dependent RNA helicase HrpA -
art_RS07050 1554354..1554605 + 252 WP_038463458.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
art_RS07055 1554602..1554859 + 258 WP_038463460.1 Txe/YoeB family addiction module toxin Toxin
art_RS07060 1554810..1556066 - 1257 WP_038463462.1 MFS transporter -
art_RS07065 1556063..1556623 - 561 WP_052136098.1 helix-turn-helix domain-containing protein -
art_RS07070 1556814..1556993 - 180 WP_038463464.1 hypothetical protein -
art_RS07075 1557404..1557889 - 486 WP_082000161.1 SDR family oxidoreductase -
art_RS07080 1558478..1558906 - 429 WP_038463466.1 HIT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10248.55 Da        Isoelectric Point: 8.0368

>T46715 WP_038463460.1 NZ_CP007595:1554602-1554859 [Arthrobacter sp. PAMC 25486]
MKLVWDEQAWAEYVDWQRDDKRVLKRINELLKDIARNGNDGIGKPEPLKHGFSGYWSRRITDEHRLVYKATGDEIRIAQC
RYHYE

Download         Length: 258 bp

>T46715 NZ_CP007595:1554602-1554859 [Arthrobacter sp. PAMC 25486]
ATGAAGTTGGTGTGGGATGAGCAGGCTTGGGCGGAATACGTTGATTGGCAACGTGACGACAAAAGAGTCCTCAAGCGCAT
CAATGAACTCCTGAAGGATATTGCCCGCAACGGGAACGACGGCATCGGCAAGCCCGAGCCGCTCAAGCACGGTTTCAGCG
GCTATTGGTCACGCAGGATCACCGACGAGCACAGGCTCGTGTACAAAGCTACCGGGGATGAAATCCGCATCGCCCAGTGC
CGGTACCACTACGAATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9109.30 Da        Isoelectric Point: 4.7513

>AT46715 WP_038463458.1 NZ_CP007595:1554354-1554605 [Arthrobacter sp. PAMC 25486]
MKTMSYSESRANYAATLDAVVNDSEEVVITRSGKEPVVIVSLVEYQSLKETAYLLRSPANARRLLGAIDRLENGSGVEHD
LLP

Download         Length: 252 bp

>AT46715 NZ_CP007595:1554354-1554605 [Arthrobacter sp. PAMC 25486]
ATGAAAACCATGAGCTATTCAGAGTCGCGGGCAAACTACGCGGCCACACTTGATGCGGTAGTGAACGACAGCGAGGAAGT
CGTGATCACCCGATCCGGGAAAGAGCCGGTGGTGATTGTCTCCCTGGTGGAGTACCAGTCATTGAAGGAAACTGCGTATC
TGTTGCGCAGCCCTGCCAACGCACGCCGCCTGTTGGGCGCCATTGACCGCTTGGAGAACGGGTCCGGCGTCGAACATGAC
CTGCTCCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0A1D0B0

Antitoxin

Source ID Structure
AlphaFold DB A0A0A1CV86

References