Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2348148..2348427 Replicon chromosome
Accession NZ_CP007499
Organism Staphylococcus aureus strain 2395 USA500

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CH51_RS12190 Protein ID WP_001802298.1
Coordinates 2348323..2348427 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2348148..2348327 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CH51_RS12170 2344347..2345012 - 666 WP_001024094.1 SDR family oxidoreductase -
CH51_RS12175 2345164..2345484 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CH51_RS12180 2345486..2346466 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CH51_RS12185 2346732..2347823 + 1092 WP_000495671.1 lytic regulatory protein -
- 2348148..2348327 + 180 - - Antitoxin
CH51_RS12190 2348323..2348427 - 105 WP_001802298.1 hypothetical protein Toxin
CH51_RS16490 2348588..2349071 - 484 Protein_2313 recombinase family protein -
CH51_RS12200 2349114..2350250 - 1137 WP_000115564.1 SAP domain-containing protein -
CH51_RS12205 2350539..2350631 + 93 WP_001790138.1 hypothetical protein -
CH51_RS12210 2351336..2352193 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
CH51_RS12215 2352261..2353043 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T46552 WP_001802298.1 NZ_CP007499:c2348427-2348323 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T46552 NZ_CP007499:c2348427-2348323 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT46552 NZ_CP007499:2348148-2348327 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References