Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2314255..2314518 Replicon chromosome
Accession NZ_CP007176
Organism Staphylococcus aureus USA300-ISMMS1

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AZ30_RS11900 Protein ID WP_001802298.1
Coordinates 2314414..2314518 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2314255..2314419 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AZ30_RS11880 2310438..2311103 - 666 WP_001024094.1 SDR family oxidoreductase -
AZ30_RS11885 2311255..2311575 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AZ30_RS11890 2311577..2312557 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
AZ30_RS11895 2312823..2313914 + 1092 WP_000495671.1 lytic regulatory protein -
- 2314255..2314419 + 165 - - Antitoxin
AZ30_RS11900 2314414..2314518 - 105 WP_001802298.1 hypothetical protein Toxin
AZ30_RS16120 2314679..2315162 - 484 Protein_2263 recombinase family protein -
AZ30_RS11910 2315205..2316341 - 1137 WP_000115564.1 SAP domain-containing protein -
AZ30_RS11915 2316630..2316722 + 93 WP_001790138.1 hypothetical protein -
AZ30_RS11920 2317427..2318284 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
AZ30_RS11925 2318352..2319134 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T46146 WP_001802298.1 NZ_CP007176:c2314518-2314414 [Staphylococcus aureus USA300-ISMMS1]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T46146 NZ_CP007176:c2314518-2314414 [Staphylococcus aureus USA300-ISMMS1]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT46146 NZ_CP007176:2314255-2314419 [Staphylococcus aureus USA300-ISMMS1]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References