Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1496243..1496501 Replicon chromosome
Accession NZ_CP007025
Organism Escherichia albertii KF1

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag EAKF1_RS07470 Protein ID WP_000809168.1
Coordinates 1496349..1496501 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 1496243..1496300 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EAKF1_RS07455 1492050..1493297 - 1248 WP_025237694.1 hypothetical protein -
EAKF1_RS07460 1493451..1494944 - 1494 WP_025237695.1 sulfatase-like hydrolase/transferase -
EAKF1_RS07465 1494965..1495726 - 762 WP_001276206.1 membrane protein -
- 1496243..1496300 - 58 - - Antitoxin
EAKF1_RS07470 1496349..1496501 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
EAKF1_RS07475 1496610..1497740 - 1131 WP_001118445.1 molecular chaperone DnaJ -
EAKF1_RS07480 1497829..1499745 - 1917 WP_000516135.1 molecular chaperone DnaK -
EAKF1_RS07485 1500120..1500524 + 405 WP_000833521.1 DUF2541 family protein -
EAKF1_RS07490 1500551..1501264 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T45858 WP_000809168.1 NZ_CP007025:1496349-1496501 [Escherichia albertii KF1]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T45858 NZ_CP007025:1496349-1496501 [Escherichia albertii KF1]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT45858 NZ_CP007025:c1496300-1496243 [Escherichia albertii KF1]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References