45292

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2484785..2484969 Replicon chromosome
Accession NZ_CP006630
Organism Staphylococcus aureus subsp. aureus SA268

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SA268_RS12645 Protein ID WP_000482647.1
Coordinates 2484862..2484969 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2484785..2484845 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA268_RS12625 2480295..2480462 - 168 WP_031845053.1 hypothetical protein -
SA268_RS12635 2480693..2482426 - 1734 WP_000488493.1 ABC transporter ATP-binding protein/permease -
SA268_RS12640 2482502..2484214 - 1713 WP_001064821.1 ABC transporter ATP-binding protein/permease -
- 2484785..2484845 + 61 - - Antitoxin
SA268_RS12645 2484862..2484969 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SA268_RS12650 2485102..2485488 - 387 WP_000779353.1 flippase GtxA -
SA268_RS12655 2485756..2486898 + 1143 WP_001176863.1 glycerate kinase -
SA268_RS12660 2486958..2487617 + 660 WP_000831298.1 membrane protein -
SA268_RS12665 2487800..2489011 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
SA268_RS12670 2489134..2489607 - 474 WP_000456483.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T45292 WP_000482647.1 NZ_CP006630:c2484969-2484862 [Staphylococcus aureus subsp. aureus SA268]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T45292 NZ_CP006630:c2484969-2484862 [Staphylococcus aureus subsp. aureus SA268]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT45292 NZ_CP006630:2484785-2484845 [Staphylococcus aureus subsp. aureus SA268]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References