Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4273255..4273909 Replicon chromosome
Accession NZ_CP005975
Organism Pseudomonas simiae strain PICF7

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PFLUOLIPICF7_RS19760 Protein ID WP_032883041.1
Coordinates 4273559..4273909 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PFLUOLIPICF7_RS19755 Protein ID WP_045791932.1
Coordinates 4273255..4273569 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PFLUOLIPICF7_RS19725 4268893..4270023 + 1131 WP_045791930.1 MFS transporter -
PFLUOLIPICF7_RS19730 4270065..4270586 - 522 WP_045791931.1 DUF3087 domain-containing protein -
PFLUOLIPICF7_RS29375 4270700..4270876 + 177 WP_010209563.1 hypothetical protein -
PFLUOLIPICF7_RS19735 4270891..4271091 + 201 WP_010209565.1 hypothetical protein -
PFLUOLIPICF7_RS19740 4271123..4271359 - 237 WP_010209566.1 hypothetical protein -
PFLUOLIPICF7_RS19745 4271480..4272307 + 828 WP_042572142.1 arylamine N-acetyltransferase -
PFLUOLIPICF7_RS19750 4272441..4273193 + 753 WP_010209570.1 outer membrane beta-barrel protein -
PFLUOLIPICF7_RS19755 4273255..4273569 - 315 WP_045791932.1 XRE family transcriptional regulator Antitoxin
PFLUOLIPICF7_RS19760 4273559..4273909 - 351 WP_032883041.1 toxin Toxin
PFLUOLIPICF7_RS19765 4274148..4275611 - 1464 WP_012724956.1 NADH-quinone oxidoreductase subunit NuoN -
PFLUOLIPICF7_RS19770 4275619..4277151 - 1533 WP_010209575.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13612.44 Da        Isoelectric Point: 9.4016

>T45145 WP_032883041.1 NZ_CP005975:c4273909-4273559 [Pseudomonas simiae]
MDALFIELPAFERHRKDYLSDELFHGFQQALMKNPEAGDVIEGTGGLRKVRFVDERRNKGQRGGLRVIYYGWSGGTQFWL
FTLYGKHEQDDLTPQHKKALKHMLDREIKARTHHET

Download         Length: 351 bp

>T45145 NZ_CP005975:c4273909-4273559 [Pseudomonas simiae]
ATGGATGCTCTATTTATCGAACTGCCGGCCTTCGAGCGGCATCGCAAGGACTATCTGAGTGACGAGCTTTTCCACGGTTT
TCAACAGGCGTTGATGAAGAACCCGGAAGCGGGAGACGTGATCGAGGGAACAGGCGGGTTACGCAAGGTTCGCTTTGTCG
ACGAACGACGCAACAAAGGCCAGCGCGGTGGCCTGCGGGTCATTTACTACGGGTGGTCAGGCGGCACGCAATTCTGGTTA
TTCACCCTGTACGGCAAACACGAACAGGACGACCTGACGCCACAGCACAAAAAAGCCCTAAAACACATGCTGGACAGGGA
AATCAAAGCGAGAACACATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11744.51 Da        Isoelectric Point: 10.4449

>AT45145 WP_045791932.1 NZ_CP005975:c4273569-4273255 [Pseudomonas simiae]
MKREIFSELVEGFDALTSERQGKVTLRTHKVHLNNLEPLTAEEVVAVRQQLNLSRAVFAMYLRTNTRTLENWEQGRAKPN
AQAATLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT45145 NZ_CP005975:c4273569-4273255 [Pseudomonas simiae]
ATGAAACGTGAAATCTTTTCCGAACTGGTCGAAGGCTTCGACGCCCTGACAAGCGAACGCCAAGGCAAAGTCACCCTGCG
GACCCACAAGGTTCATCTCAACAACCTGGAGCCGCTCACCGCAGAGGAAGTGGTCGCCGTGCGTCAACAGCTCAACCTCT
CCCGTGCCGTCTTCGCCATGTACCTGCGCACCAACACGCGTACGCTGGAGAACTGGGAGCAAGGCCGGGCTAAACCAAAT
GCCCAGGCCGCCACCCTGATTCGCCTGGTGGCGCGTTTTCCTGAGACCGTGGCACAACTTGCTGCGTTGGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References