Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2931451..2931709 Replicon chromosome
Accession NZ_CP005930
Organism Escherichia coli APEC IMT5155

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag L282_RS14545 Protein ID WP_000809168.1
Coordinates 2931451..2931603 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 2931652..2931709 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L282_RS14525 2926697..2927409 - 713 Protein_2718 acidic protein MsyB -
L282_RS14530 2927435..2927839 - 405 WP_000843687.1 DUF2541 family protein -
L282_RS14535 2928211..2930127 + 1917 WP_000516135.1 molecular chaperone DnaK -
L282_RS14540 2930216..2931346 + 1131 WP_001118464.1 molecular chaperone DnaJ -
L282_RS14545 2931451..2931603 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 2931652..2931709 + 58 - - Antitoxin
L282_RS14550 2932215..2932976 + 762 WP_001274823.1 hypothetical protein -
L282_RS14555 2932996..2934489 + 1494 WP_001350775.1 sulfatase-like hydrolase/transferase -
L282_RS14560 2934688..2935947 + 1260 WP_000494924.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T45110 WP_000809168.1 NZ_CP005930:c2931603-2931451 [Escherichia coli APEC IMT5155]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T45110 NZ_CP005930:c2931603-2931451 [Escherichia coli APEC IMT5155]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT45110 NZ_CP005930:2931652-2931709 [Escherichia coli APEC IMT5155]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References