Detailed information of TA system TA044865

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 327531..328033
• Replicon: chromosome
• Accession: NZ_CP003915
• Organism: Advenella mimigardefordensis DPN7

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: MIM_RS01500
• Protein ID: WP_025370991.1
• Coordinates: 327779..328033 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: MIM_RS01495
• Protein ID: WP_025370990.1
• Coordinates: 327531..327782 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MIM_RS21935	323114..324964	-	1851	WP_025370988.1	ATP-dependent helicase	-
MIM_RS01490	325144..327318	+	2175	WP_025370989.1	malate synthase G	-
MIM_RS01495	327531..327782	+	252	WP_025370990.1	YoeB-YefM toxin-antitoxin system antitoxin YefM	Antitoxin
MIM_RS01500	327779..328033	+	255	WP_025370991.1	Txe/YoeB family addiction module toxin	Toxin
MIM_RS01505	328171..329022	+	852	WP_025370992.1	sulfurtransferase	-
MIM_RS01510	329034..329465	-	432	WP_025370993.1	VOC family protein	-
MIM_RS01515	329791..330345	+	555	WP_144084566.1	hypothetical protein	-
MIM_RS01520	330435..332081	+	1647	WP_052342257.1	PepSY domain-containing protein	-
MIM_RS01525	332169..332975	+	807	WP_025370996.1	phosphodiester glycosidase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10091.57 Da
• Isoelectric Point: 7.3192

>T44865 WP_025370991.1 NZ_CP003915:327779-328033 [Advenella mimigardefordensis DPN7]
VKLKWSEEAWEDYLYWQDADKRMVKKINDLLNDTCRTPFEGIGKPEPLRHHLVGYWSRRITLEHRLVYAVADDALLIAAC
RYHY

Nucleotide

• Length: 255 bp

>T44865 NZ_CP003915:327779-328033 [Advenella mimigardefordensis DPN7]
GTGAAGCTGAAGTGGTCGGAAGAAGCGTGGGAAGACTATTTGTACTGGCAGGACGCCGATAAACGAATGGTTAAAAAAAT
AAACGACCTGTTGAACGATACCTGCCGTACGCCATTTGAAGGTATTGGCAAACCCGAGCCACTACGACATCATCTTGTCG
GTTATTGGTCAAGACGGATTACCTTGGAGCACAGGTTGGTCTATGCCGTGGCTGATGATGCTTTATTGATCGCCGCCTGT
CGTTATCATTATTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9246.45 Da
• Isoelectric Point: 5.0180

>AT44865 WP_025370990.1 NZ_CP003915:327531-327782 [Advenella mimigardefordensis DPN7]
MRTVSYSQARQNLSATMIQAAEDKAPVLITRQNGDACVLMSLEEYNSLQETAYLLQSPANARRLMDSIENLKSGNARERG
LIE

Nucleotide

• Length: 252 bp

>AT44865 NZ_CP003915:327531-327782 [Advenella mimigardefordensis DPN7]
ATGAGAACCGTTAGCTATAGTCAAGCCAGGCAGAACCTGTCGGCCACAATGATTCAGGCTGCAGAGGATAAGGCGCCTGT
TTTGATCACGCGCCAGAATGGCGATGCCTGCGTTCTGATGTCGCTGGAAGAATACAACTCGCTGCAGGAAACCGCTTACT
TGCTCCAGTCTCCCGCCAATGCCCGGCGATTAATGGACTCTATCGAGAATCTGAAAAGTGGTAATGCCAGAGAAAGAGGG
TTGATTGAGTGA