Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1581357..1581859 Replicon chromosome
Accession NZ_AP028142
Organism Polynucleobacter sp. HIN11

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QUE60_RS07955 Protein ID WP_286226667.1
Coordinates 1581357..1581623 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QUE60_RS07960 Protein ID WP_215370129.1
Coordinates 1581617..1581859 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE60_RS07925 (PHIN11_15340) 1577104..1578192 - 1089 WP_286226661.1 alkene reductase -
QUE60_RS07930 (PHIN11_15350) 1578256..1578456 + 201 WP_286226662.1 hypothetical protein -
QUE60_RS07935 (PHIN11_15360) 1578464..1578904 + 441 WP_286226663.1 hypothetical protein -
QUE60_RS07940 (PHIN11_15370) 1578901..1579650 + 750 WP_286226664.1 molybdate ABC transporter substrate-binding protein -
QUE60_RS07945 (PHIN11_15380) 1579775..1580281 + 507 WP_286226665.1 lipid IV(A) palmitoyltransferase PagP -
QUE60_RS07950 (PHIN11_15390) 1580293..1581216 + 924 WP_286226666.1 DUF6268 family outer membrane beta-barrel protein -
QUE60_RS07955 (PHIN11_15400) 1581357..1581623 - 267 WP_286226667.1 Txe/YoeB family addiction module toxin Toxin
QUE60_RS07960 (PHIN11_15410) 1581617..1581859 - 243 WP_215370129.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QUE60_RS07965 (PHIN11_15420) 1582400..1583611 + 1212 WP_286226669.1 tyrosine-type recombinase/integrase -
QUE60_RS07970 (PHIN11_15430) 1583637..1584017 - 381 WP_286226670.1 hypothetical protein -
QUE60_RS07975 (PHIN11_15440) 1584322..1585434 + 1113 WP_286226671.1 hypothetical protein -
QUE60_RS07980 (PHIN11_15450) 1585444..1586253 + 810 WP_286226672.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(26-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10301.00 Da        Isoelectric Point: 10.4507

>T44579 WP_286226667.1 NZ_AP028142:c1581623-1581357 [Polynucleobacter sp. HIN11]
VVAWNLAYSKFALKDAKKLSAAGLRDKAQNLLDLLAVDPFQNPPPYEKLVGDLRGAYSRRINIQHRLVYEVFRKEKTVRI
LRMWTHYD

Download         Length: 267 bp

>T44579 NZ_AP028142:c1581623-1581357 [Polynucleobacter sp. HIN11]
GTGGTAGCTTGGAATTTGGCCTATTCCAAGTTTGCCCTTAAAGACGCTAAAAAACTCTCAGCTGCTGGATTAAGAGATAA
AGCCCAGAATTTATTGGATCTATTAGCAGTAGATCCGTTTCAAAATCCGCCGCCATACGAAAAGTTGGTGGGGGATTTAA
GGGGTGCTTATTCTCGCAGAATCAATATTCAACATCGTTTAGTTTACGAGGTTTTTCGTAAAGAAAAGACTGTTCGTATT
TTGAGGATGTGGACCCACTACGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8946.35 Da        Isoelectric Point: 8.5552

>AT44579 WP_215370129.1 NZ_AP028142:c1581859-1581617 [Polynucleobacter sp. HIN11]
MTTLTASEARAGLYRLIDQTAETHKPVLISGKRSNAVLISEEDWSAIQETLYLLAIPGMRESIKESMAEPLAKSKRTLKW

Download         Length: 243 bp

>AT44579 NZ_AP028142:c1581859-1581617 [Polynucleobacter sp. HIN11]
ATGACCACATTAACCGCAAGTGAAGCGCGAGCAGGTTTATATCGCTTAATTGATCAAACTGCAGAAACACATAAGCCAGT
GCTTATTTCAGGCAAGCGCAGTAATGCCGTTTTAATTTCTGAAGAAGATTGGAGTGCCATTCAGGAAACGCTGTATCTAT
TAGCTATCCCAGGAATGCGCGAGTCCATTAAAGAATCCATGGCTGAGCCTTTGGCTAAGAGCAAAAGGACATTGAAGTGG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References