Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1581357..1581859 Replicon chromosome
Accession NZ_AP028142
Organism Polynucleobacter sp. HIN11

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QUE60_RS07955 Protein ID WP_286226667.1
Coordinates 1581357..1581623 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QUE60_RS07960 Protein ID WP_215370129.1
Coordinates 1581617..1581859 (-) Length 81 a.a.

Genomic Context


QUE60_RS07930QUE60_RS07935QUE60_RS07940QUE60_RS07945QUE60_RS07950QUE60_RS07965QUE60_RS07975QUE60_RS07980QUE60_RS07925QUE60_RS07955QUE60_RS07960QUE60_RS07970
Location: 1578256..1578456 (201 bp)
Type: Others
Protein ID: WP_286226662.1
Location: 1578464..1578904 (441 bp)
Type: Others
Protein ID: WP_286226663.1
Location: 1578901..1579650 (750 bp)
Type: Others
Protein ID: WP_286226664.1
Location: 1579775..1580281 (507 bp)
Type: Others
Protein ID: WP_286226665.1
Location: 1580293..1581216 (924 bp)
Type: Others
Protein ID: WP_286226666.1
Location: 1582400..1583611 (1212 bp)
Type: Others
Protein ID: WP_286226669.1
Location: 1584322..1585434 (1113 bp)
Type: Others
Protein ID: WP_286226671.1
Location: 1585444..1586253 (810 bp)
Type: Others
Protein ID: WP_286226672.1
Location: 1577104..1578192 (1089 bp)
Type: Others
Protein ID: WP_286226661.1
Location: 1581357..1581623 (267 bp)
Type: Toxin
Protein ID: WP_286226667.1
Location: 1581617..1581859 (243 bp)
Type: Antitoxin
Protein ID: WP_215370129.1
Location: 1583637..1584017 (381 bp)
Type: Others
Protein ID: WP_286226670.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QUE60_RS07925 (PHIN11_15340)1577104..1578192-1089WP_286226661.1alkene reductase-
QUE60_RS07930 (PHIN11_15350)1578256..1578456+201WP_286226662.1hypothetical protein-
QUE60_RS07935 (PHIN11_15360)1578464..1578904+441WP_286226663.1hypothetical protein-
QUE60_RS07940 (PHIN11_15370)1578901..1579650+750WP_286226664.1molybdate ABC transporter substrate-binding protein-
QUE60_RS07945 (PHIN11_15380)1579775..1580281+507WP_286226665.1lipid IV(A) palmitoyltransferase PagP-
QUE60_RS07950 (PHIN11_15390)1580293..1581216+924WP_286226666.1DUF6268 family outer membrane beta-barrel protein-
QUE60_RS07955 (PHIN11_15400)1581357..1581623-267WP_286226667.1Txe/YoeB family addiction module toxinToxin
QUE60_RS07960 (PHIN11_15410)1581617..1581859-243WP_215370129.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
QUE60_RS07965 (PHIN11_15420)1582400..1583611+1212WP_286226669.1tyrosine-type recombinase/integrase-
QUE60_RS07970 (PHIN11_15430)1583637..1584017-381WP_286226670.1hypothetical protein-
QUE60_RS07975 (PHIN11_15440)1584322..1585434+1113WP_286226671.1hypothetical protein-
QUE60_RS07980 (PHIN11_15450)1585444..1586253+810WP_286226672.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(26-87)

Antitoxin

(1-70)


Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10301.00 Da        Isoelectric Point: 10.4507

>T44579 WP_286226667.1 NZ_AP028142:c1581623-1581357 [Polynucleobacter sp. HIN11]
VVAWNLAYSKFALKDAKKLSAAGLRDKAQNLLDLLAVDPFQNPPPYEKLVGDLRGAYSRRINIQHRLVYEVFRKEKTVRI
LRMWTHYD

Download         Length: 267 bp

>T44579 NZ_AP028142:c1581623-1581357 [Polynucleobacter sp. HIN11]
GTGGTAGCTTGGAATTTGGCCTATTCCAAGTTTGCCCTTAAAGACGCTAAAAAACTCTCAGCTGCTGGATTAAGAGATAA
AGCCCAGAATTTATTGGATCTATTAGCAGTAGATCCGTTTCAAAATCCGCCGCCATACGAAAAGTTGGTGGGGGATTTAA
GGGGTGCTTATTCTCGCAGAATCAATATTCAACATCGTTTAGTTTACGAGGTTTTTCGTAAAGAAAAGACTGTTCGTATT
TTGAGGATGTGGACCCACTACGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8946.35 Da        Isoelectric Point: 8.5552

>AT44579 WP_215370129.1 NZ_AP028142:c1581859-1581617 [Polynucleobacter sp. HIN11]
MTTLTASEARAGLYRLIDQTAETHKPVLISGKRSNAVLISEEDWSAIQETLYLLAIPGMRESIKESMAEPLAKSKRTLKW

Download         Length: 243 bp

>AT44579 NZ_AP028142:c1581859-1581617 [Polynucleobacter sp. HIN11]
ATGACCACATTAACCGCAAGTGAAGCGCGAGCAGGTTTATATCGCTTAATTGATCAAACTGCAGAAACACATAAGCCAGT
GCTTATTTCAGGCAAGCGCAGTAATGCCGTTTTAATTTCTGAAGAAGATTGGAGTGCCATTCAGGAAACGCTGTATCTAT
TAGCTATCCCAGGAATGCGCGAGTCCATTAAAGAATCCATGGCTGAGCCTTTGGCTAAGAGCAAAAGGACATTGAAGTGG
TAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References