Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1581876..1582378 Replicon chromosome
Accession NZ_AP028141
Organism Polynucleobacter sp. HIN10

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QUE67_RS07975 Protein ID WP_286226667.1
Coordinates 1581876..1582142 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QUE67_RS07980 Protein ID WP_215370129.1
Coordinates 1582136..1582378 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE67_RS07945 (PHIN10_15350) 1577623..1578711 - 1089 WP_286226661.1 alkene reductase -
QUE67_RS07950 (PHIN10_15360) 1578775..1578975 + 201 WP_286226662.1 hypothetical protein -
QUE67_RS07955 (PHIN10_15370) 1578983..1579423 + 441 WP_286226663.1 hypothetical protein -
QUE67_RS07960 (PHIN10_15380) 1579420..1580169 + 750 WP_286226664.1 molybdate ABC transporter substrate-binding protein -
QUE67_RS07965 (PHIN10_15390) 1580294..1580800 + 507 WP_286226665.1 lipid IV(A) palmitoyltransferase PagP -
QUE67_RS07970 (PHIN10_15400) 1580812..1581735 + 924 WP_286226666.1 DUF6268 family outer membrane beta-barrel protein -
QUE67_RS07975 (PHIN10_15410) 1581876..1582142 - 267 WP_286226667.1 Txe/YoeB family addiction module toxin Toxin
QUE67_RS07980 (PHIN10_15420) 1582136..1582378 - 243 WP_215370129.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QUE67_RS07985 (PHIN10_15430) 1582919..1584130 + 1212 WP_286226669.1 tyrosine-type recombinase/integrase -
QUE67_RS07990 (PHIN10_15440) 1584156..1584536 - 381 WP_286226670.1 hypothetical protein -
QUE67_RS07995 (PHIN10_15450) 1584841..1585953 + 1113 WP_286226671.1 hypothetical protein -
QUE67_RS08000 (PHIN10_15460) 1585963..1586772 + 810 WP_286226672.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(26-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10301.00 Da        Isoelectric Point: 10.4507

>T44576 WP_286226667.1 NZ_AP028141:c1582142-1581876 [Polynucleobacter sp. HIN10]
VVAWNLAYSKFALKDAKKLSAAGLRDKAQNLLDLLAVDPFQNPPPYEKLVGDLRGAYSRRINIQHRLVYEVFRKEKTVRI
LRMWTHYD

Download         Length: 267 bp

>T44576 NZ_AP028141:c1582142-1581876 [Polynucleobacter sp. HIN10]
GTGGTAGCTTGGAATTTGGCCTATTCCAAGTTTGCCCTTAAAGACGCTAAAAAACTCTCAGCTGCTGGATTAAGAGATAA
AGCCCAGAATTTATTGGATCTATTAGCAGTAGATCCGTTTCAAAATCCGCCGCCATACGAAAAGTTGGTGGGGGATTTAA
GGGGTGCTTATTCTCGCAGAATCAATATTCAACATCGTTTAGTTTACGAGGTTTTTCGTAAAGAAAAGACTGTTCGTATT
TTGAGGATGTGGACCCACTACGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8946.35 Da        Isoelectric Point: 8.5552

>AT44576 WP_215370129.1 NZ_AP028141:c1582378-1582136 [Polynucleobacter sp. HIN10]
MTTLTASEARAGLYRLIDQTAETHKPVLISGKRSNAVLISEEDWSAIQETLYLLAIPGMRESIKESMAEPLAKSKRTLKW

Download         Length: 243 bp

>AT44576 NZ_AP028141:c1582378-1582136 [Polynucleobacter sp. HIN10]
ATGACCACATTAACCGCAAGTGAAGCGCGAGCAGGTTTATATCGCTTAATTGATCAAACTGCAGAAACACATAAGCCAGT
GCTTATTTCAGGCAAGCGCAGTAATGCCGTTTTAATTTCTGAAGAAGATTGGAGTGCCATTCAGGAAACGCTGTATCTAT
TAGCTATCCCAGGAATGCGCGAGTCCATTAAAGAATCCATGGCTGAGCCTTTGGCTAAGAGCAAAAGGACATTGAAGTGG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References