Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1581876..1582378 Replicon chromosome
Accession NZ_AP028141
Organism Polynucleobacter sp. HIN10

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QUE67_RS07975 Protein ID WP_286226667.1
Coordinates 1581876..1582142 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QUE67_RS07980 Protein ID WP_215370129.1
Coordinates 1582136..1582378 (-) Length 81 a.a.

Genomic Context


QUE67_RS07950QUE67_RS07955QUE67_RS07960QUE67_RS07965QUE67_RS07970QUE67_RS07985QUE67_RS07995QUE67_RS08000QUE67_RS07945QUE67_RS07975QUE67_RS07980QUE67_RS07990
Location: 1578775..1578975 (201 bp)
Type: Others
Protein ID: WP_286226662.1
Location: 1578983..1579423 (441 bp)
Type: Others
Protein ID: WP_286226663.1
Location: 1579420..1580169 (750 bp)
Type: Others
Protein ID: WP_286226664.1
Location: 1580294..1580800 (507 bp)
Type: Others
Protein ID: WP_286226665.1
Location: 1580812..1581735 (924 bp)
Type: Others
Protein ID: WP_286226666.1
Location: 1582919..1584130 (1212 bp)
Type: Others
Protein ID: WP_286226669.1
Location: 1584841..1585953 (1113 bp)
Type: Others
Protein ID: WP_286226671.1
Location: 1585963..1586772 (810 bp)
Type: Others
Protein ID: WP_286226672.1
Location: 1577623..1578711 (1089 bp)
Type: Others
Protein ID: WP_286226661.1
Location: 1581876..1582142 (267 bp)
Type: Toxin
Protein ID: WP_286226667.1
Location: 1582136..1582378 (243 bp)
Type: Antitoxin
Protein ID: WP_215370129.1
Location: 1584156..1584536 (381 bp)
Type: Others
Protein ID: WP_286226670.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QUE67_RS07945 (PHIN10_15350)1577623..1578711-1089WP_286226661.1alkene reductase-
QUE67_RS07950 (PHIN10_15360)1578775..1578975+201WP_286226662.1hypothetical protein-
QUE67_RS07955 (PHIN10_15370)1578983..1579423+441WP_286226663.1hypothetical protein-
QUE67_RS07960 (PHIN10_15380)1579420..1580169+750WP_286226664.1molybdate ABC transporter substrate-binding protein-
QUE67_RS07965 (PHIN10_15390)1580294..1580800+507WP_286226665.1lipid IV(A) palmitoyltransferase PagP-
QUE67_RS07970 (PHIN10_15400)1580812..1581735+924WP_286226666.1DUF6268 family outer membrane beta-barrel protein-
QUE67_RS07975 (PHIN10_15410)1581876..1582142-267WP_286226667.1Txe/YoeB family addiction module toxinToxin
QUE67_RS07980 (PHIN10_15420)1582136..1582378-243WP_215370129.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
QUE67_RS07985 (PHIN10_15430)1582919..1584130+1212WP_286226669.1tyrosine-type recombinase/integrase-
QUE67_RS07990 (PHIN10_15440)1584156..1584536-381WP_286226670.1hypothetical protein-
QUE67_RS07995 (PHIN10_15450)1584841..1585953+1113WP_286226671.1hypothetical protein-
QUE67_RS08000 (PHIN10_15460)1585963..1586772+810WP_286226672.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(26-87)

Antitoxin

(1-70)


Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10301.00 Da        Isoelectric Point: 10.4507

>T44576 WP_286226667.1 NZ_AP028141:c1582142-1581876 [Polynucleobacter sp. HIN10]
VVAWNLAYSKFALKDAKKLSAAGLRDKAQNLLDLLAVDPFQNPPPYEKLVGDLRGAYSRRINIQHRLVYEVFRKEKTVRI
LRMWTHYD

Download         Length: 267 bp

>T44576 NZ_AP028141:c1582142-1581876 [Polynucleobacter sp. HIN10]
GTGGTAGCTTGGAATTTGGCCTATTCCAAGTTTGCCCTTAAAGACGCTAAAAAACTCTCAGCTGCTGGATTAAGAGATAA
AGCCCAGAATTTATTGGATCTATTAGCAGTAGATCCGTTTCAAAATCCGCCGCCATACGAAAAGTTGGTGGGGGATTTAA
GGGGTGCTTATTCTCGCAGAATCAATATTCAACATCGTTTAGTTTACGAGGTTTTTCGTAAAGAAAAGACTGTTCGTATT
TTGAGGATGTGGACCCACTACGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8946.35 Da        Isoelectric Point: 8.5552

>AT44576 WP_215370129.1 NZ_AP028141:c1582378-1582136 [Polynucleobacter sp. HIN10]
MTTLTASEARAGLYRLIDQTAETHKPVLISGKRSNAVLISEEDWSAIQETLYLLAIPGMRESIKESMAEPLAKSKRTLKW

Download         Length: 243 bp

>AT44576 NZ_AP028141:c1582378-1582136 [Polynucleobacter sp. HIN10]
ATGACCACATTAACCGCAAGTGAAGCGCGAGCAGGTTTATATCGCTTAATTGATCAAACTGCAGAAACACATAAGCCAGT
GCTTATTTCAGGCAAGCGCAGTAATGCCGTTTTAATTTCTGAAGAAGATTGGAGTGCCATTCAGGAAACGCTGTATCTAT
TAGCTATCCCAGGAATGCGCGAGTCCATTAAAGAATCCATGGCTGAGCCTTTGGCTAAGAGCAAAAGGACATTGAAGTGG
TAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References