Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 389962..390590 Replicon chromosome
Accession NZ_AP028138
Organism Polynucleobacter sp. HIN7

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QUE64_RS02015 Protein ID WP_286225705.1
Coordinates 390267..390590 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QUE64_RS02010 Protein ID WP_286225704.1
Coordinates 389962..390270 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE64_RS01990 (PHIN7_03810) 385719..387641 + 1923 WP_286225701.1 1-deoxy-D-xylulose-5-phosphate synthase -
QUE64_RS01995 (PHIN7_03820) 387699..388523 + 825 WP_286225702.1 GTP cyclohydrolase FolE2 -
QUE64_RS02000 (PHIN7_03830) 388520..389590 - 1071 WP_286225703.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD -
QUE64_RS02005 (PHIN7_03840) 389677..389889 + 213 WP_011903537.1 30S ribosomal protein S21 -
QUE64_RS02010 (PHIN7_03850) 389962..390270 - 309 WP_286225704.1 helix-turn-helix transcriptional regulator Antitoxin
QUE64_RS02015 (PHIN7_03860) 390267..390590 - 324 WP_286225705.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUE64_RS02020 (PHIN7_03870) 390734..391180 + 447 WP_286224121.1 GatB/YqeY domain-containing protein -
QUE64_RS02025 (PHIN7_03880) 391197..393083 + 1887 WP_286226144.1 DNA primase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-97)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12303.65 Da        Isoelectric Point: 10.3519

>T44568 WP_286225705.1 NZ_AP028138:c390590-390267 [Polynucleobacter sp. HIN7]
MKYSIIYYSQEVQEAIMNLPVTLQARYIGLTDRMMEHGPNLGLPHTDAFGGGLFELRLKGAEGIARVFFCLAVKQKIVML
HSFIKKTQKTPDKELKLAKQRMKEFKK

Download         Length: 324 bp

>T44568 NZ_AP028138:c390590-390267 [Polynucleobacter sp. HIN7]
ATGAAATACTCTATCATTTATTACAGTCAAGAGGTTCAGGAAGCAATCATGAATTTACCAGTTACGCTTCAAGCTCGATA
TATCGGCTTAACTGACCGAATGATGGAGCATGGACCCAACTTAGGCTTACCTCATACCGATGCATTTGGAGGTGGCCTAT
TTGAACTAAGGCTTAAAGGTGCAGAGGGTATTGCGCGCGTTTTCTTTTGCTTAGCTGTAAAACAAAAAATTGTCATGCTC
CATAGCTTTATAAAGAAAACTCAAAAGACCCCCGATAAAGAATTAAAGCTTGCCAAGCAACGCATGAAGGAGTTTAAGAA
ATGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11105.04 Da        Isoelectric Point: 11.1790

>AT44568 WP_286225704.1 NZ_AP028138:c390270-389962 [Polynucleobacter sp. HIN7]
MTTKSTKALTHKQMVNKMLKNSAVKAELNRLNREELSILDEILAARKEAGLSQAQVAKRMGTQAPAIARLESALASGKHS
PSLSTLRKYAAALGKRIELHLV

Download         Length: 309 bp

>AT44568 NZ_AP028138:c390270-389962 [Polynucleobacter sp. HIN7]
ATGACAACCAAATCGACTAAAGCGCTGACCCACAAACAAATGGTCAACAAGATGCTTAAGAATTCTGCTGTTAAAGCTGA
ACTTAATCGACTTAACCGCGAAGAGCTATCAATTTTGGATGAGATTCTTGCTGCCAGAAAAGAAGCGGGGCTATCACAAG
CTCAGGTTGCAAAACGCATGGGCACCCAAGCGCCAGCCATTGCAAGGCTAGAAAGCGCTCTGGCCTCTGGAAAACATTCT
CCAAGCCTTAGCACGCTGCGCAAATATGCTGCCGCCTTAGGTAAGCGCATTGAGCTTCATTTGGTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References