Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
| Location | 2562632..2563203 | Replicon | chromosome |
| Accession | NZ_AP028062 | ||
| Organism | Marinobacter shengliensis strain D49 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | QUE75_RS11770 | Protein ID | WP_230714988.1 |
| Coordinates | 2562925..2563203 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | A0A137S7I0 |
| Locus tag | QUE75_RS11765 | Protein ID | WP_061332719.1 |
| Coordinates | 2562632..2562925 (-) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUE75_RS11725 (MAALD49_23260) | 2557901..2559109 | + | 1209 | WP_286250294.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| QUE75_RS11730 (MAALD49_23270) | 2559241..2560551 | + | 1311 | WP_286250296.1 | methyl-accepting chemotaxis protein | - |
| QUE75_RS11735 (MAALD49_23280) | 2560595..2561200 | - | 606 | WP_106695971.1 | hypothetical protein | - |
| QUE75_RS11740 (MAALD49_23290) | 2561308..2561424 | - | 117 | Protein_2296 | type II toxin-antitoxin system YoeB family toxin | - |
| QUE75_RS11745 (MAALD49_23300) | 2561420..2561662 | - | 243 | WP_061332723.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| QUE75_RS11750 (MAALD49_23310) | 2561870..2562064 | + | 195 | WP_061332722.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| QUE75_RS11755 (MAALD49_23320) | 2562061..2562312 | + | 252 | WP_286250300.1 | hypothetical protein | - |
| QUE75_RS11760 (MAALD49_23330) | 2562364..2562564 | + | 201 | WP_230714989.1 | BrnA antitoxin family protein | - |
| QUE75_RS11765 (MAALD49_23340) | 2562632..2562925 | - | 294 | WP_061332719.1 | HigA family addiction module antitoxin | Antitoxin |
| QUE75_RS11770 (MAALD49_23350) | 2562925..2563203 | - | 279 | WP_230714988.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| QUE75_RS11775 (MAALD49_23360) | 2563316..2563618 | - | 303 | WP_061332717.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| QUE75_RS11780 (MAALD49_23370) | 2563606..2563863 | - | 258 | WP_022992576.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| QUE75_RS11785 (MAALD49_23380) | 2564006..2564305 | - | 300 | WP_016914159.1 | helix-turn-helix domain-containing protein | - |
| QUE75_RS11790 (MAALD49_23390) | 2564298..2564612 | - | 315 | WP_286250317.1 | transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10721.21 Da Isoelectric Point: 9.8061
>T44462 WP_230714988.1 NZ_AP028062:c2563203-2562925 [Marinobacter shengliensis]
MIKSFRHKGLKRFYSTGSTSGIQPDHPKKLRMQLAALDTATSVDDMDIPGFRLHPLKGLDKGRWSIWVSGNWRMTFEFRD
GNAYILDYEDYH
MIKSFRHKGLKRFYSTGSTSGIQPDHPKKLRMQLAALDTATSVDDMDIPGFRLHPLKGLDKGRWSIWVSGNWRMTFEFRD
GNAYILDYEDYH
Download Length: 279 bp
>T44462 NZ_AP028062:c2563203-2562925 [Marinobacter shengliensis]
ATGATTAAATCATTCCGTCACAAAGGACTGAAGCGGTTCTACTCGACCGGCAGCACGTCTGGCATACAGCCAGATCATCC
CAAGAAACTGCGCATGCAGCTGGCAGCTCTGGATACCGCCACTTCGGTGGATGATATGGATATCCCTGGTTTTCGGCTTC
ACCCATTGAAGGGGCTAGACAAAGGGCGGTGGTCGATTTGGGTAAGCGGAAACTGGCGCATGACGTTCGAATTTCGGGAC
GGCAACGCCTACATACTTGATTATGAGGATTATCACTAA
ATGATTAAATCATTCCGTCACAAAGGACTGAAGCGGTTCTACTCGACCGGCAGCACGTCTGGCATACAGCCAGATCATCC
CAAGAAACTGCGCATGCAGCTGGCAGCTCTGGATACCGCCACTTCGGTGGATGATATGGATATCCCTGGTTTTCGGCTTC
ACCCATTGAAGGGGCTAGACAAAGGGCGGTGGTCGATTTGGGTAAGCGGAAACTGGCGCATGACGTTCGAATTTCGGGAC
GGCAACGCCTACATACTTGATTATGAGGATTATCACTAA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10709.29 Da Isoelectric Point: 6.7217
>AT44462 WP_061332719.1 NZ_AP028062:c2562925-2562632 [Marinobacter shengliensis]
MTMHNPPHPGEFIREVYLAPFGISSRQLASSLGVSPSTLSRLLKGNSGISPEMSLRLSKVLGRTPESWLAMQDMYDLWVA
RNTVNLDGIHPLDFEAA
MTMHNPPHPGEFIREVYLAPFGISSRQLASSLGVSPSTLSRLLKGNSGISPEMSLRLSKVLGRTPESWLAMQDMYDLWVA
RNTVNLDGIHPLDFEAA
Download Length: 294 bp
>AT44462 NZ_AP028062:c2562925-2562632 [Marinobacter shengliensis]
ATGACCATGCATAATCCGCCACATCCCGGTGAATTCATTCGGGAGGTGTACCTGGCGCCTTTCGGTATCAGTTCCCGTCA
GCTTGCTTCCAGTCTGGGCGTATCACCTTCCACTTTGTCTCGGTTGCTCAAAGGAAATAGTGGTATTAGCCCGGAAATGT
CATTGCGGCTATCCAAGGTTCTCGGGCGTACTCCTGAGAGCTGGTTGGCAATGCAGGACATGTACGATCTTTGGGTGGCC
CGCAATACGGTCAATCTGGATGGCATTCATCCCCTGGACTTCGAAGCAGCTTAA
ATGACCATGCATAATCCGCCACATCCCGGTGAATTCATTCGGGAGGTGTACCTGGCGCCTTTCGGTATCAGTTCCCGTCA
GCTTGCTTCCAGTCTGGGCGTATCACCTTCCACTTTGTCTCGGTTGCTCAAAGGAAATAGTGGTATTAGCCCGGAAATGT
CATTGCGGCTATCCAAGGTTCTCGGGCGTACTCCTGAGAGCTGGTTGGCAATGCAGGACATGTACGATCTTTGGGTGGCC
CGCAATACGGTCAATCTGGATGGCATTCATCCCCTGGACTTCGAAGCAGCTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|