Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 280920..281323 Replicon chromosome
Accession NZ_AP027370
Organism Hydrogenimonas sp. ISO32

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QUD54_RS01390 Protein ID WP_286337175.1
Coordinates 280920..281183 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QUD54_RS01395 Protein ID WP_286337176.1
Coordinates 281180..281323 (-) Length 48 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD54_RS01365 (HCR_02700) 276361..276744 + 384 WP_286337170.1 type III-A CRISPR-associated protein Csm2 -
QUD54_RS01370 (HCR_02710) 276773..277408 + 636 WP_286337171.1 type III-A CRISPR-associated RAMP protein Csm3 -
QUD54_RS01375 (HCR_02720) 277412..278296 + 885 WP_286337172.1 hypothetical protein -
QUD54_RS01380 (HCR_02730) 278293..279594 + 1302 WP_286337173.1 type III-A CRISPR-associated RAMP protein Csm5 -
QUD54_RS01385 (HCR_02740) 279594..280829 + 1236 WP_286337174.1 TIGR02221 family CRISPR-associated protein -
QUD54_RS01390 (HCR_02750) 280920..281183 - 264 WP_286337175.1 Txe/YoeB family addiction module toxin Toxin
QUD54_RS01395 (HCR_02760) 281180..281323 - 144 WP_286337176.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QUD54_RS01400 281317..281442 - 126 WP_286337177.1 hypothetical protein -
QUD54_RS01405 281599..281739 + 141 WP_286337178.1 hypothetical protein -
QUD54_RS01410 (HCR_02770) 281729..283624 + 1896 WP_286337179.1 DNA recombination protein RmuC -
QUD54_RS01415 (HCR_02780) 283682..283951 + 270 WP_286337180.1 CRISPR-associated endonuclease Cas2 -
QUD54_RS01420 (HCR_02790) 283948..284814 + 867 WP_286337181.1 CRISPR-associated endonuclease Cas1 -
QUD54_RS01425 (HCR_02800) 284811..285050 + 240 WP_286337182.1 hypothetical protein -
QUD54_RS01430 (HCR_02810) 285047..285325 + 279 WP_286337183.1 CRISPR-associated endonuclease Cas2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-37)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10336.06 Da        Isoelectric Point: 9.3490

>T43777 WP_286337175.1 NZ_AP027370:c281183-280920 [Hydrogenimonas sp. ISO32]
MIVAFSSIGWEDYLYWQCTYKRVLKRINTLIKDIVRNPDDVNGLGKPLMLKGNLSGYFSRRITDEHRLVYKIDGDYLIVA
QCRFHYM

Download         Length: 264 bp

>T43777 NZ_AP027370:c281183-280920 [Hydrogenimonas sp. ISO32]
ATGATCGTCGCCTTCTCCTCCATCGGATGGGAGGATTATCTCTACTGGCAGTGCACCTACAAACGCGTGCTCAAACGGAT
CAACACACTCATCAAAGATATCGTCCGCAATCCCGACGACGTGAACGGCCTCGGCAAGCCTTTAATGCTAAAAGGCAATC
TGAGCGGTTACTTTTCCAGGCGCATCACCGACGAGCATCGGCTGGTTTATAAAATTGACGGAGATTATCTCATCGTCGCG
CAGTGCCGGTTTCATTATATGTAA

Antitoxin


Download         Length: 48 a.a.        Molecular weight: 5686.49 Da        Isoelectric Point: 4.1773

>AT43777 WP_286337176.1 NZ_AP027370:c281323-281180 [Hydrogenimonas sp. ISO32]
MLISVDEYRSMKETLYLLSTPANRERLLQWIEEIETGRFDPKELIEE

Download         Length: 144 bp

>AT43777 NZ_AP027370:c281323-281180 [Hydrogenimonas sp. ISO32]
ATGCTGATATCGGTCGACGAATACCGATCGATGAAAGAGACGCTCTATCTGCTTTCCACACCCGCCAACCGGGAGAGACT
GCTTCAATGGATCGAAGAGATCGAAACGGGACGATTCGACCCCAAAGAGCTGATAGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References