Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | txpA-ratA/- |
| Location | 947457..947731 | Replicon | chromosome |
| Accession | NZ_AP027302 | ||
| Organism | Enterococcus faecalis strain N4E | ||
Toxin (Protein)
| Gene name | txpA | Uniprot ID | S4BYM2 |
| Locus tag | QUD80_RS04560 | Protein ID | WP_002392696.1 |
| Coordinates | 947457..947600 (+) | Length | 48 a.a. |
Antitoxin (RNA)
| Gene name | ratA | ||
| Locus tag | - | ||
| Coordinates | 947533..947731 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUD80_RS04535 (944190) | 944190..944744 | + | 555 | WP_002354869.1 | Maf family protein | - |
| QUD80_RS04540 (944877) | 944877..945314 | + | 438 | WP_002354871.1 | peptide-methionine (R)-S-oxide reductase MsrB | - |
| QUD80_RS04545 (945489) | 945489..946460 | + | 972 | WP_002381060.1 | ribose-phosphate diphosphokinase | - |
| QUD80_RS04550 (946513) | 946513..946719 | - | 207 | WP_258075960.1 | CPBP family intramembrane metalloprotease | - |
| QUD80_RS04555 (946924) | 946924..947049 | + | 126 | WP_002383214.1 | hypothetical protein | - |
| QUD80_RS04560 (947457) | 947457..947600 | + | 144 | WP_002392696.1 | type I toxin-antitoxin system toxin PepG1 | Toxin |
| - (947574) | 947574..947719 | - | 146 | NuclAT_14 | - | - |
| - (947533) | 947533..947731 | - | 199 | NuclAT_9 | - | Antitoxin |
| QUD80_RS04565 (947832) | 947832..947975 | + | 144 | WP_002392696.1 | type I toxin-antitoxin system toxin PepG1 | - |
| - (947908) | 947908..948094 | - | 187 | NuclAT_10 | - | - |
| - (947949) | 947949..948094 | - | 146 | NuclAT_13 | - | - |
| - (948141) | 948141..948274 | - | 134 | NuclAT_15 | - | - |
| QUD80_RS04570 (948343) | 948343..948993 | - | 651 | WP_002354875.1 | beta-phosphoglucomutase | - |
| QUD80_RS04575 (949008) | 949008..951752 | - | 2745 | WP_174113967.1 | glycoside hydrolase family 65 protein | - |
| QUD80_RS04580 (952013) | 952013..952726 | + | 714 | WP_002354877.1 | trehalose operon repressor | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 48 a.a. Molecular weight: 5297.43 Da Isoelectric Point: 10.6867
>T43745 WP_002392696.1 NZ_AP027302:947457-947600 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
Download Length: 144 bp
>T43745 NZ_AP027302:947457-947600 [Enterococcus faecalis]
ATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTGTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGG
TATGTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAATAAAAAATAA
ATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTGTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGG
TATGTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAATAAAAAATAA
Antitoxin
Download Length: 199 bp
>AT43745 NZ_AP027302:c947731-947533 [Enterococcus faecalis]
TTTTTAGGGAAATGTGCTATAATGAAAATGAAAAGAGAGATATGCTTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGA
CGGTGACCGATTATATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATT
TCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA
TTTTTAGGGAAATGTGCTATAATGAAAATGAAAAGAGAGATATGCTTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGA
CGGTGACCGATTATATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATT
TCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
