43743

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-RNAII/-
Location 856495..856758 Replicon chromosome
Accession NZ_AP027302
Organism Enterococcus faecalis strain N4E

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag QUD80_RS04130 Protein ID WP_002389461.1
Coordinates 856615..856758 (-) Length 48 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 856495..856641 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
- (856048) 856048..856097 - 50 NuclAT_16 - -
- (856047) 856047..856309 + 263 NuclAT_11 - -
QUD80_RS04125 (856241) 856241..856384 - 144 WP_016619108.1 putative holin-like toxin -
- (856495) 856495..856641 + 147 NuclAT_12 - Antitoxin
- (856481) 856481..856682 + 202 NuclAT_8 - -
QUD80_RS04130 (856615) 856615..856758 - 144 WP_002389461.1 type I toxin-antitoxin system toxin PepG1 Toxin
QUD80_RS04135 (857093) 857093..858709 - 1617 WP_174114069.1 phosphatase PAP2/LCP family protein -
QUD80_RS04140 (859395) 859395..860033 + 639 WP_002378863.1 lytic polysaccharide monooxygenase -
QUD80_RS04145 (860200) 860200..861192 - 993 WP_002378862.1 biotin--[acetyl-CoA-carboxylase] ligase -
QUD80_RS04150 (861331) 861331..861546 + 216 WP_002354768.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5450.67 Da        Isoelectric Point: 11.0942

>T43743 WP_002389461.1 NZ_AP027302:c856758-856615 [Enterococcus faecalis]
MHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 144 bp

>T43743 NZ_AP027302:c856758-856615 [Enterococcus faecalis]
ATGCACGTATTTCCGAAATTCAGAGAAAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGG
TATGTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin


Download         Length: 147 bp

>AT43743 NZ_AP027302:856495-856641 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCTTT
TTGATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References