Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 447522..447716 Replicon chromosome
Accession NZ_AP027302
Organism Enterococcus faecalis strain N4E

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag QUD80_RS02155 Protein ID WP_015543884.1
Coordinates 447522..447617 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 447652..447716 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD80_RS02135 (442701) 442701..443816 + 1116 WP_033785759.1 FAD-dependent oxidoreductase -
QUD80_RS02140 (443883) 443883..445037 - 1155 WP_002395429.1 mannitol-1-phosphate 5-dehydrogenase -
QUD80_RS02145 (445052) 445052..445489 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
QUD80_RS02150 (445504) 445504..447276 - 1773 WP_002387897.1 PTS mannitol-specific transporter subunit IIBC -
QUD80_RS02155 (447522) 447522..447617 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- (447652) 447652..447716 - 65 NuclAT_17 - Antitoxin
QUD80_RS02160 (447886) 447886..448320 - 435 WP_002358391.1 PTS sugar transporter subunit IIA -
QUD80_RS02165 (448331) 448331..450364 - 2034 WP_002361171.1 PRD domain-containing protein -
QUD80_RS02170 (450355) 450355..452096 - 1742 Protein_430 PTS transporter subunit EIIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T43731 WP_015543884.1 NZ_AP027302:447522-447617 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T43731 NZ_AP027302:447522-447617 [Enterococcus faecalis]
ATGTACGAGATTGTCACAAAAATTCTTGTGCCGATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA

Antitoxin


Download         Length: 65 bp

>AT43731 NZ_AP027302:c447716-447652 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References