43728

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 268886..269118 Replicon chromosome
Accession NZ_AP027302
Organism Enterococcus faecalis strain N4E

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag QUD80_RS01300 Protein ID WP_002355568.1
Coordinates 269002..269118 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 268886..269091 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD80_RS01280 (264373) 264373..265461 - 1089 WP_002355572.1 diacylglycerol kinase -
QUD80_RS01285 (265480) 265480..266910 - 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
QUD80_RS01290 (266910) 266910..268379 - 1470 WP_002358701.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
QUD80_RS01295 (268379) 268379..268684 - 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
- (268886) 268886..269091 + 206 NuclAT_3 - Antitoxin
QUD80_RS01300 (269002) 269002..269118 - 117 WP_002355568.1 putative holin-like toxin Toxin
QUD80_RS01305 (269266) 269266..271296 - 2031 WP_002364804.1 NAD-dependent DNA ligase LigA -
QUD80_RS01310 (271422) 271422..273680 - 2259 WP_002364805.1 DNA helicase PcrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T43728 WP_002355568.1 NZ_AP027302:c269118-269002 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

>T43728 NZ_AP027302:c269118-269002 [Enterococcus faecalis]
ATGTTTTTGTCCGTTGAAGCAGCGCTAGGACTGATGATTGGTTTTGCAACACTTGTTGTGACCATTATCTTCGGTATCTT
AGCGCTTGTCTTAGACAACAAAAATAACCGTTCATAA

Antitoxin


Download         Length: 206 bp

>AT43728 NZ_AP027302:268886-269091 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References