Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 1332480..1332706 Replicon chromosome
Accession NZ_AP027297
Organism Enterococcus faecalis strain L6D

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag QUD71_RS06500 Protein ID WP_219843903.1
Coordinates 1332480..1332590 (+) Length 37 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 1332501..1332706 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD71_RS06490 (1327912) 1327912..1330170 + 2259 WP_010708284.1 DNA helicase PcrA -
QUD71_RS06495 (1330296) 1330296..1332326 + 2031 WP_286328466.1 NAD-dependent DNA ligase LigA -
QUD71_RS06500 (1332480) 1332480..1332590 + 111 WP_219843903.1 putative holin-like toxin Toxin
QUD71_RS06505 (1332908) 1332908..1333213 + 306 WP_010819759.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
QUD71_RS06510 (1333213) 1333213..1334682 + 1470 WP_010819760.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
QUD71_RS06515 (1334682) 1334682..1336112 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
QUD71_RS06520 (1336131) 1336131..1337219 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-33)


Sequences

Toxin        


Download         Length: 37 a.a.        Molecular weight: 3805.59 Da        Isoelectric Point: 5.9482

>T43719 WP_219843903.1 NZ_AP027297:1332480-1332590 [Enterococcus faecalis]
MSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 111 bp

>T43719 NZ_AP027297:1332480-1332590 [Enterococcus faecalis]
TTGTCCGTTGAAGCAGCGCTAGGACTGATGATTGGTTTTGCAACACTTGTTGTGACCATTATCTTCGGTATCTTAGCGCT
TGTCTTAGACAACAAAAATAACCGTTCATAA

Antitoxin


Download         Length: 206 bp

>AT43719 NZ_AP027297:c1332706-1332501 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACCAGTTATAAGAACTGGTGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References