Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 745318..745579 Replicon chromosome
Accession NZ_AP027297
Organism Enterococcus faecalis strain L6D

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag QUD71_RS03585 Protein ID WP_286328473.1
Coordinates 745318..745461 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 745394..745579 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD71_RS03570 741035..741667 - 633 WP_002358972.1 RloB family protein -
QUD71_RS03575 741676..742971 - 1296 WP_010820355.1 ATP-binding protein -
QUD71_RS03580 743433..745049 + 1617 WP_010820356.1 phosphatase PAP2/LCP family protein -
QUD71_RS03585 745318..745461 + 144 WP_286328473.1 type I toxin-antitoxin system toxin PepG1 Toxin
- 745394..745579 - 186 - - Antitoxin
QUD71_RS03590 745608..745745 + 138 WP_286328474.1 putative holin-like toxin -
QUD71_RS03595 746134..750000 - 3867 WP_010820360.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5381.51 Da        Isoelectric Point: 10.6868

>T43710 WP_286328473.1 NZ_AP027297:745318-745461 [Enterococcus faecalis]
MHVFPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Download         Length: 144 bp

>T43710 NZ_AP027297:745318-745461 [Enterococcus faecalis]
ATGCACGTATTTCCGAAATTCACAGAAAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGG
TATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATTGCTTAAAAATGACAATAAAAAATAA

Antitoxin


Download         Length: 186 bp

>AT43710 NZ_AP027297:c745579-745394 [Enterococcus faecalis]
TGCTACAATAGAAACGAAAAGAGAGGTATGCTGTAACATACCTCTCTAATGTAGAACCGTTTAAGACGGTGACCATGTTA
ATTATTTAAAAATAACCGTACTCGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATTTCACAATCAGCGC
AATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References