Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3942067..3942289 Replicon chromosome
Accession NZ_AP027254
Organism Escherichia coli strain JNE120442

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag QUE31_RS19635 Protein ID WP_001295224.1
Coordinates 3942067..3942174 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3942223..3942289 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE31_RS19610 3937320..3938072 - 753 WP_000279544.1 cellulose biosynthesis protein BcsQ -
QUE31_RS19615 3938084..3938272 - 189 WP_001063315.1 cellulose biosynthesis protein BcsR -
QUE31_RS19620 3938545..3940116 + 1572 WP_001204944.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
QUE31_RS19625 3940113..3940304 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
QUE31_RS19630 3940301..3941980 + 1680 WP_001562264.1 cellulose biosynthesis protein BcsG -
QUE31_RS19635 3942067..3942174 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 3942223..3942289 + 67 - - Antitoxin
QUE31_RS19640 3942650..3943921 + 1272 WP_001318103.1 aromatic amino acid transport family protein -
QUE31_RS19645 3943951..3944955 - 1005 WP_000107036.1 dipeptide ABC transporter ATP-binding subunit DppF -
QUE31_RS19650 3944952..3945935 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
QUE31_RS19655 3945946..3946848 - 903 WP_016238586.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T43605 WP_001295224.1 NZ_AP027254:c3942174-3942067 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T43605 NZ_AP027254:c3942174-3942067 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT43605 NZ_AP027254:3942223-3942289 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References