Detailed information of TA system TA043475

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 890616..891315
• Replicon: chromosome
• Accession: NZ_AP027203
• Organism: Polynucleobacter sp. SHI2

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: QMN13_RS04585
• Protein ID: WP_281971359.1
• Coordinates: 890616..890912 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: QMN13_RS04590
• Protein ID: WP_281971360.1
• Coordinates: 890914..891315 (+)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QMN13_RS04565 (PSHI2_08950)	886374..886805	+	432	WP_281971355.1	cell division protein FtsB	-
QMN13_RS04570 (PSHI2_08960)	886809..887810	-	1002	WP_281971356.1	Hsp33 family molecular chaperone HslO	-
QMN13_RS04575 (PSHI2_08970)	887859..889094	+	1236	WP_281971357.1	YbfB/YjiJ family MFS transporter	-
QMN13_RS04580 (PSHI2_08980)	889127..890554	+	1428	WP_281971358.1	glutamate--tRNA ligase	-
QMN13_RS04585 (PSHI2_08990)	890616..890912	+	297	WP_281971359.1	type II toxin-antitoxin system MqsR family toxin	Toxin
QMN13_RS04590 (PSHI2_09000)	890914..891315	+	402	WP_281971360.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
QMN13_RS04610 (PSHI2_09010)	892047..892637	+	591	WP_281971361.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (5-97)

Antitoxin

• Cro/C1-type helix-turn-helix domain (74-117)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11449.61 Da
• Isoelectric Point: 9.9844

>T43475 WP_281971359.1 NZ_AP027203:890616-890912 [Polynucleobacter sp. SHI2]
MEKSTPHCKLIIVKRLLVQKKVMISNVAYEGAARLGLDKSDIIKIVSELTPKQFYKSMTTYKDHKIWQDVYRTKFDEINI
YLKITVIEQVAVVSFKEL

Nucleotide

• Length: 297 bp

>T43475 NZ_AP027203:890616-890912 [Polynucleobacter sp. SHI2]
ATGGAAAAATCAACACCACACTGTAAGTTAATTATTGTTAAAAGATTGTTAGTACAGAAAAAAGTCATGATTTCAAATGT
GGCTTATGAAGGAGCTGCTAGGTTGGGTTTGGATAAGTCGGACATCATAAAAATTGTTAGTGAATTAACGCCAAAGCAAT
TCTATAAAAGTATGACTACCTATAAGGACCATAAAATTTGGCAAGATGTTTATAGAACGAAATTTGATGAGATAAATATT
TATTTAAAAATTACAGTTATTGAGCAAGTTGCTGTCGTATCCTTTAAGGAGTTATAA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 15174.61 Da
• Isoelectric Point: 9.1144

>AT43475 WP_281971360.1 NZ_AP027203:890914-891315 [Polynucleobacter sp. SHI2]
MKCPSCGGAQLITDTRDYPYQYKNQTIIFKKIKGDYCDSCGEVYFNDIDGQKFNAKLLKFNKKVNESLFDPSLISRVRKK
LNLDQKEAGKIFGGGVNAFSRYENGKSKPPIALIKLFFILDQYPELLELINCV

Nucleotide

• Length: 402 bp

>AT43475 NZ_AP027203:890914-891315 [Polynucleobacter sp. SHI2]
ATGAAATGTCCCAGTTGTGGTGGAGCACAATTAATCACTGATACCAGAGATTACCCCTATCAATACAAAAACCAAACCAT
CATCTTTAAAAAAATTAAAGGGGATTATTGCGATTCATGCGGTGAGGTTTACTTTAACGATATTGACGGTCAAAAATTTA
ACGCAAAATTATTGAAATTTAATAAAAAAGTGAATGAAAGTTTGTTTGACCCTAGTTTGATATCTAGAGTGCGAAAAAAA
TTGAATTTAGATCAAAAAGAAGCTGGAAAAATATTTGGAGGGGGCGTCAACGCATTTTCTAGATATGAAAACGGCAAATC
AAAACCACCCATCGCCTTGATTAAGCTATTTTTTATCTTGGATCAATACCCAGAACTTTTAGAATTAATTAACTGTGTAT
AA