Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | ralRA/- |
| Location | 1886900..1887271 | Replicon | chromosome |
| Accession | NZ_AP027197 | ||
| Organism | Escherichia coli strain 02E060 | ||
Toxin (Protein)
| Gene name | ralR | Uniprot ID | A0A0D6ZRD3 |
| Locus tag | QMG97_RS09960 | Protein ID | WP_001443846.1 |
| Coordinates | 1887122..1887271 (-) | Length | 50 a.a. |
Antitoxin (RNA)
| Gene name | ralA | ||
| Locus tag | - | ||
| Coordinates | 1886900..1887078 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG97_RS09930 (1882652) | 1882652..1882825 | + | 174 | WP_001443847.1 | protein YnaL | - |
| QMG97_RS09935 (1882855) | 1882855..1884228 | + | 1374 | WP_000123745.1 | ATP-dependent RNA helicase DbpA | - |
| QMG97_RS09940 (1884357) | 1884357..1885292 | - | 936 | WP_001157407.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
| QMG97_RS09945 (1885344) | 1885344..1886579 | - | 1236 | WP_000040851.1 | site-specific integrase | - |
| QMG97_RS09950 (1886581) | 1886581..1886796 | - | 216 | WP_000079604.1 | excisionase XisR | - |
| - (1886900) | 1886900..1887078 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (1886900) | 1886900..1887078 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (1886900) | 1886900..1887078 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (1886900) | 1886900..1887078 | + | 179 | NuclAT_0 | - | Antitoxin |
| QMG97_RS09955 (1886896) | 1886896..1887084 | - | 189 | WP_001302840.1 | DUF1187 family protein | - |
| QMG97_RS09960 (1887122) | 1887122..1887271 | - | 150 | WP_001443846.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
| QMG97_RS09965 (1887327) | 1887327..1888136 | - | 810 | WP_000166313.1 | recombination protein RecT | - |
| QMG97_RS09970 (1888129) | 1888129..1890729 | - | 2601 | WP_000105151.1 | exodeoxyribonuclease VIII | - |
| QMG97_RS09975 (1890831) | 1890831..1891106 | - | 276 | WP_000632297.1 | protein RacC | - |
| QMG97_RS09980 (1891181) | 1891181..1891351 | - | 171 | WP_001352098.1 | YdaE family protein | - |
| QMG97_RS09985 (1891351) | 1891351..1891572 | - | 222 | WP_000560223.1 | killing protein KilR | - |
| QMG97_RS09990 (1891993) | 1891993..1892145 | - | 153 | WP_001427316.1 | DUF1391 family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1885344..1931180 | 45836 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 50 a.a. Molecular weight: 5383.12 Da Isoelectric Point: 8.3398
>T43442 WP_001443846.1 NZ_AP027197:c1887271-1887122 [Escherichia coli]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALER
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALER
Download Length: 150 bp
>T43442 NZ_AP027197:c1887271-1887122 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAACGATGA
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAACGATGA
Antitoxin
Download Length: 179 bp
>AT43442 NZ_AP027197:1886900-1887078 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
