43012

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 467506..467738 Replicon chromosome
Accession NZ_AP027136
Organism Enterococcus faecalis strain JARB-HU0796

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag QUD94_RS02310 Protein ID WP_002355568.1
Coordinates 467506..467622 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 467533..467738 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD94_RS02300 (462944) 462944..465202 + 2259 WP_078122705.1 DNA helicase PcrA -
QUD94_RS02305 (465328) 465328..467358 + 2031 WP_010710796.1 NAD-dependent DNA ligase LigA -
QUD94_RS02310 (467506) 467506..467622 + 117 WP_002355568.1 putative holin-like toxin Toxin
- (467533) 467533..467738 - 206 NuclAT_2 - Antitoxin
QUD94_RS02315 (467940) 467940..468245 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
QUD94_RS02320 (468245) 468245..469714 + 1470 WP_002368026.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
QUD94_RS02325 (469714) 469714..471144 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
QUD94_RS02330 (471163) 471163..472251 + 1089 WP_002396964.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T43012 WP_002355568.1 NZ_AP027136:467506-467622 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

>T43012 NZ_AP027136:467506-467622 [Enterococcus faecalis]
ATGTTTTTGTCCGTTGAAGCAGCGTTGGGACTGATGATTGGTTTTGCAACACTTGTTGTGACCATTATCTTCGGTATCTT
AGCGCTTGTCTTAGACAACAAAAATAACCGTTCATAA

Antitoxin


Download         Length: 206 bp

>AT43012 NZ_AP027136:c467738-467533 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References