Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2197276..2197492 Replicon chromosome
Accession NZ_AP027135
Organism Staphylococcus aureus strain JP089

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QMM73_RS10975 Protein ID WP_001802298.1
Coordinates 2197388..2197492 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2197276..2197331 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMM73_RS10950 2193473..2194138 - 666 WP_001024089.1 SDR family oxidoreductase -
QMM73_RS10955 2194290..2194610 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QMM73_RS10960 2194612..2195589 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
QMM73_RS10965 2195855..2196946 + 1092 WP_061838836.1 hypothetical protein -
- 2197276..2197331 + 56 - - Antitoxin
QMM73_RS10975 2197388..2197492 - 105 WP_001802298.1 hypothetical protein Toxin
QMM73_RS10980 2198172..2198330 + 159 WP_001792784.1 hypothetical protein -
QMM73_RS10985 2198988..2199845 - 858 WP_000370924.1 HAD family hydrolase -
QMM73_RS10990 2199913..2200695 - 783 WP_061838837.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T43004 WP_001802298.1 NZ_AP027135:c2197492-2197388 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T43004 NZ_AP027135:c2197492-2197388 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT43004 NZ_AP027135:2197276-2197331 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References