Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2189586..2189802 Replicon chromosome
Accession NZ_AP027134
Organism Staphylococcus aureus strain JP008

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QMM94_RS10815 Protein ID WP_001802298.1
Coordinates 2189698..2189802 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2189586..2189641 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMM94_RS10790 2185717..2186382 - 666 WP_001024097.1 SDR family oxidoreductase -
QMM94_RS10795 2186534..2186854 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QMM94_RS10800 2186856..2187836 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
QMM94_RS10805 2188102..2189193 + 1092 WP_154284124.1 transcriptional regulator -
- 2189586..2189641 + 56 - - Antitoxin
QMM94_RS10815 2189698..2189802 - 105 WP_001802298.1 hypothetical protein Toxin
QMM94_RS10820 2190482..2190640 + 159 WP_001792784.1 hypothetical protein -
QMM94_RS10825 2191298..2192155 - 858 WP_154284123.1 HAD family hydrolase -
QMM94_RS10830 2192223..2193005 - 783 WP_267814087.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T42989 WP_001802298.1 NZ_AP027134:c2189802-2189698 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T42989 NZ_AP027134:c2189802-2189698 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT42989 NZ_AP027134:2189586-2189641 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References