Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 738125..738698 Replicon chromosome
Accession NZ_AP027055
Organism Limnohabitans sp. INBF002

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QMG15_RS03740 Protein ID WP_281789571.1
Coordinates 738426..738698 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QMG15_RS03735 Protein ID WP_281789570.1
Coordinates 738125..738433 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG15_RS03705 (LINBF2_07370) 734102..735283 - 1182 WP_281789564.1 acetyl-CoA C-acyltransferase family protein -
QMG15_RS03710 (LINBF2_07380) 735346..736026 - 681 WP_281789565.1 RluA family pseudouridine synthase -
QMG15_RS03715 (LINBF2_07390) 736039..736344 - 306 WP_281789566.1 2Fe-2S iron-sulfur cluster-binding protein -
QMG15_RS03720 (LINBF2_07400) 736354..736632 - 279 WP_281789567.1 hypothetical protein -
QMG15_RS03725 (LINBF2_07410) 736810..737349 - 540 WP_281789568.1 pseudouridine synthase -
QMG15_RS03730 (LINBF2_07420) 737428..738120 + 693 WP_281789569.1 SOS response-associated peptidase family protein -
QMG15_RS03735 (LINBF2_07430) 738125..738433 - 309 WP_281789570.1 helix-turn-helix transcriptional regulator Antitoxin
QMG15_RS03740 (LINBF2_07440) 738426..738698 - 273 WP_281789571.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMG15_RS03745 (LINBF2_07450) 738889..739380 - 492 WP_281789572.1 hypothetical protein -
QMG15_RS03750 (LINBF2_07460) 739384..741216 - 1833 WP_281789573.1 glutamine--tRNA ligase/YqeY domain fusion protein -
QMG15_RS03755 (LINBF2_07470) 741245..741946 - 702 WP_281789574.1 ABC transporter ATP-binding protein -
QMG15_RS03760 (LINBF2_07480) 741939..743207 - 1269 WP_281789575.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 736039..745954 9915


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(2-85)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-97)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 9942.64 Da        Isoelectric Point: 10.2257

>T42972 WP_281789571.1 NZ_AP027055:c738698-738426 [Limnohabitans sp. INBF002]
MPAGIAADYLRLTEAMALYGADLRMPHSRAMGGGLFELRPKGPEGIGRVFYCTQVGKTIVVLHSFVKKTQETPDAEMRVA
RKRLKDVQHG

Download         Length: 273 bp

>T42972 NZ_AP027055:c738698-738426 [Limnohabitans sp. INBF002]
ATGCCAGCGGGCATCGCGGCTGACTATCTGCGACTGACCGAAGCGATGGCACTCTACGGCGCAGACCTTCGCATGCCGCA
CTCACGCGCGATGGGCGGCGGTTTGTTTGAGCTGCGCCCGAAAGGGCCAGAAGGAATTGGGCGGGTGTTTTATTGCACGC
AAGTGGGCAAGACCATTGTGGTGCTGCACTCGTTCGTGAAGAAAACACAAGAAACACCAGACGCAGAAATGCGCGTGGCA
CGCAAACGATTAAAGGATGTGCAACATGGCTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10992.75 Da        Isoelectric Point: 10.1599

>AT42972 WP_281789570.1 NZ_AP027055:c738433-738125 [Limnohabitans sp. INBF002]
MANNGYKPVPHDAAFKKALLAKPGVKKAYDALEEEYSTLHAMLDARLAAGLTQADVAARMGTTVSAISRLESSLRSEKHS
PSFATLRKYAQACGKKLVVQMV

Download         Length: 309 bp

>AT42972 NZ_AP027055:c738433-738125 [Limnohabitans sp. INBF002]
ATGGCTAACAACGGATACAAACCCGTGCCGCATGATGCGGCTTTTAAAAAGGCATTGCTTGCCAAGCCTGGCGTGAAGAA
AGCCTATGACGCGCTGGAAGAGGAATATTCCACGCTGCACGCCATGCTCGATGCGCGTTTGGCTGCGGGCCTCACTCAAG
CCGATGTGGCTGCGCGCATGGGCACCACGGTGTCGGCTATTTCTCGGCTTGAATCGTCGCTGCGCAGCGAAAAACACTCA
CCCTCTTTTGCCACGCTGCGCAAGTACGCACAAGCCTGCGGCAAAAAGCTGGTGGTGCAGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References