Detailed information of TA system TA042625

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 17350..17593
• Replicon: plasmid pSVR2330_1
• Accession: NZ_AP026722
• Organism: Enterococcus faecalis strain SVR2330

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: PO855_RS16035
• Protein ID: WP_002387930.1
• Coordinates: 17492..17593 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	17350..17452 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PO855_RS16020 (13061)	13061..16047	+	2987	Protein_13	Tn3 family transposase	-
PO855_RS16025 (16231)	16231..16521	-	291	WP_002365947.1	hypothetical protein	-
PO855_RS16030 (16692)	16692..17153	-	462	WP_002365946.1	hypothetical protein	-
- (17350)	17350..17452	+	103	NuclAT_0	-	Antitoxin
- (17350)	17350..17452	+	103	NuclAT_0	-	Antitoxin
- (17350)	17350..17452	+	103	NuclAT_0	-	Antitoxin
- (17350)	17350..17452	+	103	NuclAT_0	-	Antitoxin
PO855_RS16035 (17492)	17492..17593	-	102	WP_002387930.1	type I toxin-antitoxin system Fst family toxin	Toxin
PO855_RS16040 (17684)	17684..17896	-	213	WP_002365945.1	hypothetical protein	-
PO855_RS16045 (17853)	17853..18203	-	351	WP_002365943.1	hypothetical protein	-
PO855_RS16050 (18200)	18200..19528	-	1329	WP_002387639.1	ultraviolet resistance protein UvrA	-
PO855_RS16055 (19955)	19955..20107	-	153	WP_225850000.1	DUF6440 family protein	-
PO855_RS16060 (20269)	20269..20478	-	210	WP_002387638.1	hypothetical protein	-
PO855_RS16065 (20539)	20539..20763	-	225	WP_010708492.1	ultraviolet resistance protein UvrA repressor UvrC	-
PO855_RS16070 (20757)	20757..21044	-	288	WP_010708491.1	hypothetical protein	-
PO855_RS16075 (21061)	21061..21681	-	621	WP_021732893.1	recombinase family protein	-
PO855_RS16080 (22211)	22211..22417	-	207	Protein_25	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	prgB/asc10	1..73523	73523

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3731.42 Da
• Isoelectric Point: 4.1672

>T42625 WP_002387930.1 NZ_AP026722:c17593-17492 [Enterococcus faecalis]
VKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 102 bp

>T42625 NZ_AP026722:c17593-17492 [Enterococcus faecalis]
GTGAAAGATTTAATGTCGTTGGTTATCGCACCAATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGTGTTGGACGA
GGAAGACGATAGCCGAAAGTAA

Antitoxin

Nucleotide

• Length: 103 bp

>AT42625 NZ_AP026722:17350-17452 [Enterococcus faecalis]
TTGACCCAAAATAAAAATATGCTATACTAAAAGTGCGAAACGACATTAAATCGTACAGATAACACAAAAAGCAATCCTAC
GGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin