Detailed information of TA system TA042616

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2905857..2906117
• Replicon: chromosome
• Accession: NZ_AP026721
• Organism: Enterococcus faecalis strain SVR2330

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: PO855_RS14395
• Protein ID: WP_075551663.1
• Coordinates: 2906016..2906117 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2905857..2906067 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PO855_RS14370	2901541..2902494	-	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-
PO855_RS14375	2902533..2903288	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
PO855_RS14380	2903285..2904250	-	966	WP_002354961.1	iron chelate uptake ABC transporter family permease subunit	-
PO855_RS14385	2904247..2905194	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
PO855_RS14390	2905379..2905831	+	453	WP_002354958.1	YueI family protein	-
-	2905857..2906067	+	211	-	-	Antitoxin
PO855_RS14395	2906016..2906117	-	102	WP_075551663.1	putative holin-like toxin	Toxin
PO855_RS14400	2906306..2908578	-	2273	Protein_2814	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
PO855_RS14405	2908749..2909249	+	501	WP_002370089.1	cysteine hydrolase family protein	-
PO855_RS14410	2909552..2910448	+	897	WP_002368434.1	YitT family protein	-
PO855_RS14415	2910499..2910897	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T42616 WP_075551663.1 NZ_AP026721:c2906117-2906016 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

>T42616 NZ_AP026721:c2906117-2906016 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA

Antitoxin

Nucleotide

• Length: 211 bp

>AT42616 NZ_AP026721:2905857-2906067 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAGCG
CCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGT
TATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin