Detailed information of TA system TA042605

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 1490274..1490791
• Replicon: chromosome
• Accession: NZ_AP026708
• Organism: Pseudodesulfovibrio portus strain JCM 14722

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: OO730_RS07210
• Protein ID: WP_264983907.1
• Coordinates: 1490274..1490534 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: OO730_RS07215
• Protein ID: WP_264983908.1
• Coordinates: 1490534..1490791 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OO730_RS07185 (JCM14722_13910)	1486149..1486700	+	552	WP_264983902.1	biotin transporter BioY	-
OO730_RS07190 (JCM14722_13920)	1486716..1487507	+	792	WP_264983903.1	PTS system mannose/fructose/sorbose family transporter subunit IID	-
OO730_RS07195 (JCM14722_13930)	1487557..1487859	+	303	WP_264983904.1	HPr family phosphocarrier protein	-
OO730_RS07200 (JCM14722_13940)	1487863..1489647	+	1785	WP_264983905.1	phosphoenolpyruvate--protein phosphotransferase	-
OO730_RS07205 (JCM14722_13950)	1489651..1490133	+	483	WP_264983906.1	SsrA-binding protein SmpB	-
OO730_RS07210 (JCM14722_13960)	1490274..1490534	-	261	WP_264983907.1	Txe/YoeB family addiction module toxin	Toxin
OO730_RS07215 (JCM14722_13970)	1490534..1490791	-	258	WP_264983908.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
OO730_RS07220 (JCM14722_13980)	1490883..1491524	-	642	WP_264983909.1	ribonuclease HII	-
OO730_RS07225 (JCM14722_13990)	1491769..1492119	-	351	WP_264983910.1	50S ribosomal protein L19	-
OO730_RS07230 (JCM14722_14000)	1492137..1493432	-	1296	WP_264983911.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
OO730_RS07235 (JCM14722_14010)	1493429..1494028	-	600	WP_264983912.1	ribosome maturation factor RimM	-
OO730_RS07240 (JCM14722_14020)	1494041..1494274	-	234	WP_015414977.1	KH domain-containing protein	-
OO730_RS07245 (JCM14722_14030)	1494379..1494618	-	240	WP_264983913.1	30S ribosomal protein S16	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (4-74)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10593.12 Da
• Isoelectric Point: 9.3150

>T42605 WP_264983907.1 NZ_AP026708:c1490534-1490274 [Pseudodesulfovibrio portus]
MRLTWTEHGWEDYLYWQKADKKMVKRINLLIRDALRTPFEGRGKPEPLRFDLTGYWSRRIDREHRLVYAYDSEADALIIA
QCRYHY

Nucleotide

• Length: 261 bp

>T42605 NZ_AP026708:c1490534-1490274 [Pseudodesulfovibrio portus]
ATGCGCCTCACCTGGACCGAACACGGTTGGGAAGATTATCTGTATTGGCAGAAGGCCGACAAAAAGATGGTCAAGCGCAT
CAATCTGCTCATCCGGGACGCCCTGAGGACTCCCTTTGAAGGGCGGGGCAAGCCCGAACCGCTCCGTTTCGACCTCACCG
GCTACTGGTCCCGCCGCATCGACAGGGAACACCGCCTTGTCTACGCCTACGACAGCGAGGCGGACGCACTGATCATCGCC
CAATGCCGTTACCACTACTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9424.59 Da
• Isoelectric Point: 4.4791

>AT42605 WP_264983908.1 NZ_AP026708:c1490791-1490534 [Pseudodesulfovibrio portus]
MPEAITYTDARQRLASTMDEVCDSHEPVIITRRKAKSVVMMSLEDYNSIAETAYLLGSPANADRLRASIRSAQAGELEEH
ALLED

Nucleotide

• Length: 258 bp

>AT42605 NZ_AP026708:c1490791-1490534 [Pseudodesulfovibrio portus]
ATGCCCGAAGCCATCACCTACACCGATGCTCGTCAACGCCTGGCGTCCACCATGGACGAGGTGTGCGATTCGCATGAGCC
CGTGATCATCACGCGGCGCAAGGCAAAGTCTGTGGTCATGATGTCCCTGGAAGACTATAATTCGATCGCTGAAACGGCGT
ATCTGCTAGGCAGCCCGGCCAATGCCGACCGGTTGCGTGCGTCAATCCGTTCCGCCCAGGCGGGGGAGCTTGAAGAACAC
GCGCTCCTGGAGGACTGA