Detailed information of TA system TA040836

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 1733686..1734057
• Replicon: chromosome
• Accession: NZ_AP025754
• Organism: Escherichia sp. KS167_9B strain KS-P079

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: -
• Locus tag: QUE34_RS08730
• Protein ID: WP_042966159.1
• Coordinates: 1733863..1734057 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	1733686..1733864 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QUE34_RS08700 (1729437)	1729437..1729610	+	174	WP_001296046.1	protein YnaL	-
QUE34_RS08705 (1729641)	1729641..1731014	+	1374	WP_000123713.1	ATP-dependent RNA helicase DbpA	-
QUE34_RS08710 (1731143)	1731143..1732078	-	936	WP_105268606.1	tRNA 2-thiocytidine(32) synthetase TtcA	-
QUE34_RS08715 (1732130)	1732130..1733365	-	1236	WP_072034645.1	site-specific integrase	-
QUE34_RS08720 (1733367)	1733367..1733582	-	216	WP_000079604.1	excisionase XisR	-
- (1733686)	1733686..1733864	+	179	NuclAT_0	-	Antitoxin
- (1733686)	1733686..1733864	+	179	NuclAT_0	-	Antitoxin
- (1733686)	1733686..1733864	+	179	NuclAT_0	-	Antitoxin
- (1733686)	1733686..1733864	+	179	NuclAT_0	-	Antitoxin
QUE34_RS08725 (1733682)	1733682..1733870	-	189	WP_001356607.1	DUF1187 family protein	-
QUE34_RS08730 (1733863)	1733863..1734057	-	195	WP_042966159.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
QUE34_RS08735 (1734121)	1734121..1735209	-	1089	WP_042966158.1	RecT family recombinase	-
QUE34_RS08740 (1735224)	1735224..1738370	-	3147	WP_042966157.1	exodeoxyribonuclease VIII	-
QUE34_RS08745 (1738472)	1738472..1738747	-	276	WP_001358843.1	hypothetical protein	-
QUE34_RS08750 (1738822)	1738822..1738998	-	177	WP_000258918.1	YdaE family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	paa	1732130..1781920	49790

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7047.97 Da
• Isoelectric Point: 8.9492

>T40836 WP_042966159.1 NZ_AP025754:c1734057-1733863 [Escherichia sp. KS167_9B]
MRYEKVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNDNGGVHV

Nucleotide

• Length: 195 bp

>T40836 NZ_AP025754:c1734057-1733863 [Escherichia sp. KS167_9B]
ATGCGGTATGAAAAAGTCAAACCATGTCCGTTTTGTGGTTGTCCATCAGTAACGGTTAAAGCTATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATGATAATGGAGGTGTTCATGTATAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT40836 NZ_AP025754:1733686-1733864 [Escherichia sp. KS167_9B]
GAGGACAGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Structures

Antitoxin