40641

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2197600..2197816 Replicon chromosome
Accession NZ_AP025683
Organism Staphylococcus aureus strain JP025

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag SAJP025_RS10785 Protein ID WP_073392962.1
Coordinates 2197712..2197816 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2197600..2197655 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAJP025_RS10760 2193794..2194459 - 666 WP_248535966.1 SDR family oxidoreductase -
SAJP025_RS10765 2194611..2194931 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAJP025_RS10770 2194933..2195913 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
SAJP025_RS10775 2196179..2197270 + 1092 WP_029264569.1 hypothetical protein -
- 2197600..2197655 + 56 - - Antitoxin
SAJP025_RS10785 2197712..2197816 - 105 WP_073392962.1 hypothetical protein Toxin
SAJP025_RS10790 2198496..2198654 + 159 WP_078091561.1 integrase -
SAJP025_RS10795 2199313..2200170 - 858 WP_000370937.1 HAD family hydrolase -
SAJP025_RS10800 2200238..2201020 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(7-48)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T40641 WP_073392962.1 NZ_AP025683:c2197816-2197712 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T40641 NZ_AP025683:c2197816-2197712 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT40641 NZ_AP025683:2197600-2197655 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References