Detailed information of TA system TA040633

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1890744..1890924
• Replicon: chromosome
• Accession: NZ_AP025683
• Organism: Staphylococcus aureus strain JP025

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAJP025_RS09065
• Protein ID: WP_001801861.1
• Coordinates: 1890744..1890839 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1890867..1890924 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAJP025_RS09035	1885888..1886514	+	627	WP_000669038.1	hypothetical protein	-
SAJP025_RS09040	1886555..1886899	+	345	WP_000627550.1	DUF3969 family protein	-
SAJP025_RS09045	1886997..1887569	+	573	WP_000414222.1	hypothetical protein	-
SAJP025_RS09050	1887718..1889085	-	1368	WP_001093573.1	FRG domain-containing protein	-
SAJP025_RS09055	1889085..1889654	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
SAJP025_RS09060	1889847..1890293	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
SAJP025_RS09065	1890744..1890839	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1890867..1890924	-	58	-	-	Antitoxin
SAJP025_RS09070	1890962..1891063	+	102	WP_001791232.1	hypothetical protein	-
SAJP025_RS09075	1891238..1891681	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
SAJP025_RS09080	1891681..1892124	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
SAJP025_RS09085	1892124..1892566	-	443	Protein_1790	DUF1433 domain-containing protein	-
SAJP025_RS09090	1893091..1895511	+	2421	WP_000182551.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T40633 WP_001801861.1 NZ_AP025683:1890744-1890839 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T40633 NZ_AP025683:1890744-1890839 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT40633 NZ_AP025683:c1890924-1890867 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin