Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 188593..188815 Replicon chromosome
Accession NZ_AP025675
Organism Escherichia coli strain Rb-3

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag MWM15_RS00890 Protein ID WP_001295224.1
Coordinates 188708..188815 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 188593..188659 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MWM15_RS00870 184034..184936 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
MWM15_RS00875 184947..185930 + 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
MWM15_RS00880 185927..186931 + 1005 WP_000103577.1 dipeptide ABC transporter ATP-binding subunit DppF -
MWM15_RS00885 186961..188232 - 1272 WP_001298005.1 aromatic amino acid transport family protein -
- 188593..188659 - 67 - - Antitoxin
MWM15_RS00890 188708..188815 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
MWM15_RS00895 188902..190581 - 1680 WP_000191565.1 cellulose biosynthesis protein BcsG -
MWM15_RS00900 190578..190769 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
MWM15_RS00905 190766..192337 - 1572 WP_001204945.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
MWM15_RS00910 192610..192798 + 189 WP_001063314.1 cellulose biosynthesis protein BcsR -
MWM15_RS00915 192810..193562 + 753 WP_000279536.1 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T40541 WP_001295224.1 NZ_AP025675:188708-188815 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T40541 NZ_AP025675:188708-188815 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT40541 NZ_AP025675:c188659-188593 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References