40468

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1533623..1534167 Replicon chromosome
Accession NZ_AP025637
Organism Roseomonas fluvialis strain S08

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MWM08_RS07510 Protein ID WP_244458839.1
Coordinates 1533623..1533895 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MWM08_RS07515 Protein ID WP_244458840.1
Coordinates 1533892..1534167 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MWM08_RS07475 (Rmf_14990) 1528930..1529343 + 414 WP_244458834.1 DUF3830 family protein -
MWM08_RS07485 (Rmf_15000) 1529520..1530047 + 528 WP_244458835.1 hypothetical protein -
MWM08_RS07490 (Rmf_15010) 1530273..1531196 + 924 WP_244459921.1 Ppx/GppA family phosphatase -
MWM08_RS07495 (Rmf_15020) 1531390..1532073 + 684 WP_244458836.1 RlmE family RNA methyltransferase -
MWM08_RS07500 1532559..1533248 + 690 WP_244458837.1 hypothetical protein -
MWM08_RS07505 1533320..1533472 + 153 WP_244458838.1 hypothetical protein -
MWM08_RS07510 (Rmf_15060) 1533623..1533895 - 273 WP_244458839.1 Txe/YoeB family addiction module toxin Toxin
MWM08_RS07515 (Rmf_15070) 1533892..1534167 - 276 WP_244458840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MWM08_RS07520 (Rmf_15080) 1534419..1535924 + 1506 WP_244458841.1 IMP dehydrogenase -
MWM08_RS07525 (Rmf_15090) 1536098..1536775 + 678 WP_244458842.1 haloacid dehalogenase type II -
MWM08_RS07530 (Rmf_15100) 1536772..1538124 + 1353 WP_244458843.1 RsmB/NOP family class I SAM-dependent RNA methyltransferase -
MWM08_RS07535 (Rmf_15110) 1538121..1538699 + 579 WP_244458844.1 GNAT family N-acetyltransferase -
MWM08_RS07540 (Rmf_15120) 1538703..1538885 - 183 WP_244458845.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10695.04 Da        Isoelectric Point: 8.5126

>T40468 WP_244458839.1 NZ_AP025637:c1533895-1533623 [Roseomonas fluvialis]
VKVWFTAEGWEDYLHWTTTDRDTHQRINDMIEDTRRHPCTGLGKPEPLKGPLAGFWSRRITREHRLVYRVAGKAGEDQRI
EVVQCRYHYG

Download         Length: 273 bp

>T40468 NZ_AP025637:c1533895-1533623 [Roseomonas fluvialis]
GTGAAGGTCTGGTTCACGGCCGAAGGCTGGGAGGACTACCTGCACTGGACCACCACCGACCGCGACACCCACCAGCGCAT
CAACGACATGATCGAGGACACGCGCCGCCACCCCTGCACGGGGCTCGGCAAGCCGGAACCGCTGAAGGGACCGCTGGCGG
GGTTCTGGTCGCGACGCATCACGCGGGAGCACCGGCTGGTGTACCGCGTGGCAGGGAAGGCGGGGGAGGACCAGCGGATC
GAGGTGGTGCAGTGTAGGTATCACTATGGGTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9906.25 Da        Isoelectric Point: 8.7721

>AT40468 WP_244458840.1 NZ_AP025637:c1534167-1533892 [Roseomonas fluvialis]
MSTLSYTELRSNLARTMDEAIATRDAILVTRQGGKGNVVLMAEAEFRSWQETIHLLSAPANAARLLRSVASAEAGDAAER
DLAPPPRTLRR

Download         Length: 276 bp

>AT40468 NZ_AP025637:c1534167-1533892 [Roseomonas fluvialis]
ATGAGCACGTTGTCCTACACCGAACTGCGCAGCAACCTCGCCCGCACCATGGACGAGGCCATTGCCACCCGCGACGCCAT
CCTGGTCACCCGCCAGGGCGGCAAGGGCAACGTCGTCCTGATGGCCGAGGCCGAATTCCGGTCCTGGCAGGAAACCATCC
ACCTGCTCTCCGCCCCGGCCAACGCGGCGCGGCTGCTGCGGTCCGTCGCGTCGGCCGAGGCCGGCGACGCCGCCGAGCGC
GACCTGGCCCCGCCCCCGCGCACCCTCCGCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References