Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 884835..885652 Replicon chromosome
Accession NZ_AP025556
Organism Delftia lacustris strain HQS1

Toxin (Protein)


Gene name yhaV Uniprot ID A0A6N8S4E7
Locus tag HQS1_RS03990 Protein ID WP_034363310.1
Coordinates 884835..885326 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A031I1Z5
Locus tag HQS1_RS03995 Protein ID WP_016452695.1
Coordinates 885323..885652 (-) Length 110 a.a.

Genomic Context

HQS1_RS03960HQS1_RS03965HQS1_RS03970HQS1_RS03975HQS1_RS03980HQS1_RS03985HQS1_RS04015HQS1_RS04020HQS1_RS03990HQS1_RS03995HQS1_RS04000HQS1_RS04005HQS1_RS04010
Location: 879961..880446 (486 bp)
Type: Others
Protein ID: WP_026062693.1
Location: 880443..881321 (879 bp)
Type: Others
Protein ID: WP_244387787.1
Location: 881318..882115 (798 bp)
Type: Others
Protein ID: WP_034363307.1
Location: 882179..882508 (330 bp)
Type: Others
Protein ID: WP_013800515.1
Location: 882784..884193 (1410 bp)
Type: Others
Protein ID: WP_244387788.1
Location: 884308..884820 (513 bp)
Type: Others
Protein ID: WP_016448386.1
Location: 889271..890101 (831 bp)
Type: Others
Protein ID: WP_141835639.1
Location: 890191..890460 (270 bp)
Type: Others
Protein ID: WP_012207631.1
Location: 884835..885326 (492 bp)
Type: Toxin
Protein ID: WP_034363310.1
Location: 885323..885652 (330 bp)
Type: Antitoxin
Protein ID: WP_016452695.1
Location: 885750..887990 (2241 bp)
Type: Others
Protein ID: WP_244387789.1
Location: 888114..888509 (396 bp)
Type: Others
Protein ID: WP_034363313.1
Location: 888538..889200 (663 bp)
Type: Others
Protein ID: WP_034363316.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HQS1_RS03960 (HQS1_07780)879961..880446+486WP_026062693.1cobalamin biosynthesis protein-
HQS1_RS03965 (HQS1_07790)880443..881321+879WP_244387787.1precorrin-4 C(11)-methyltransferase-
HQS1_RS03970 (HQS1_07800)881318..882115+798WP_034363307.1precorrin-6A synthase (deacetylating)-
HQS1_RS03975 (HQS1_07810)882179..882508+330WP_013800515.1DHCW motif cupin fold protein-
HQS1_RS03980 (HQS1_07820)882784..884193+1410WP_244387788.1chloride channel protein-
HQS1_RS03985 (HQS1_07830)884308..884820+513WP_016448386.1MgtC/SapB family protein-
HQS1_RS03990 (HQS1_07840)884835..885326-492WP_034363310.1type II toxin-antitoxin system YhaV family toxinToxin
HQS1_RS03995 (HQS1_07850)885323..885652-330WP_016452695.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
HQS1_RS04000 (HQS1_07860)885750..887990-2241WP_244387789.1TonB-dependent receptor-
HQS1_RS04005 (HQS1_07870)888114..888509-396WP_034363313.1hypothetical protein-
HQS1_RS04010 (HQS1_07880)888538..889200-663WP_034363316.1pyridoxamine 5'-phosphate oxidase family protein-
HQS1_RS04015 (HQS1_07890)889271..890101+831WP_141835639.1helix-turn-helix transcriptional regulator-
HQS1_RS04020 (HQS1_07900)890191..890460+270WP_012207631.1type II toxin-antitoxin system ParD family antitoxin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18763.37 Da        Isoelectric Point: 10.2214

>T40417 WP_034363310.1 NZ_AP025556:c885326-884835 [Delftia lacustris]
MSAVPPAPLRIHGWTVFMHPLFLAQLQALSQEVEGLKTKDPGGYTRKNATKRLAAIRKLAFDVIPQDPTRPDYRQGHTLG
EEHKHWFRARFFQQYRLFFRFHAPSKIIVFAWVNDEDTKRAYEGSDDAYRVFRKMLANGHPPGDWDSLLAQAKSPPPDSQ
PHA

Download         Length: 492 bp

>T40417 NZ_AP025556:c885326-884835 [Delftia lacustris]
ATGAGCGCCGTACCGCCCGCCCCCTTGCGCATCCACGGCTGGACGGTATTCATGCACCCGCTTTTCCTGGCCCAGCTGCA
GGCGTTGAGCCAGGAAGTGGAGGGTCTGAAAACCAAGGACCCTGGCGGGTACACACGCAAGAACGCGACCAAGCGATTGG
CGGCGATCCGCAAGCTGGCATTCGATGTCATCCCGCAGGATCCGACGCGGCCAGACTACCGCCAGGGCCATACCCTGGGC
GAGGAGCACAAGCACTGGTTTCGGGCCAGGTTCTTCCAGCAGTACCGCCTGTTCTTTCGCTTTCACGCCCCCAGCAAAAT
CATCGTGTTCGCCTGGGTCAACGATGAGGACACCAAGCGAGCCTATGAGGGCAGCGACGATGCCTACAGGGTGTTCCGAA
AAATGCTCGCCAACGGGCACCCTCCTGGCGATTGGGACAGTTTGCTGGCACAGGCGAAGTCCCCGCCACCCGACTCACAG
CCGCACGCCTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12036.45 Da        Isoelectric Point: 4.1858

>AT40417 WP_016452695.1 NZ_AP025556:c885652-885323 [Delftia lacustris]
MFSTLEAESTLTDRYQTTIPEAVRRALHLSKRDRIHYTILPGGEVVLSRADSAEDADPVLGQFLGFLAQDMAAHPERLQT
MDARLAQQIQALTEGIEVDLDAPLSADDE

Download         Length: 330 bp

>AT40417 NZ_AP025556:c885652-885323 [Delftia lacustris]
ATGTTTTCGACACTTGAAGCCGAATCCACGCTCACTGACCGCTACCAGACCACCATTCCCGAAGCCGTTCGCCGCGCATT
GCACCTGAGCAAGCGCGACAGGATCCACTACACCATCCTGCCCGGCGGTGAGGTCGTTCTCAGTCGCGCCGACTCCGCCG
AGGATGCCGATCCCGTGCTGGGCCAGTTTCTCGGCTTTCTGGCACAGGACATGGCAGCCCACCCCGAGCGCCTGCAGACC
ATGGATGCCCGTCTGGCGCAGCAGATCCAGGCGCTGACCGAAGGCATCGAGGTCGATCTGGATGCACCGCTTTCGGCAGA
CGACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A6N8S4E7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A031I1Z5

References