Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 3302882..3303509 Replicon chromosome
Accession NZ_AP025483
Organism Vibrio echinoideorum strain DSM 107264

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OCV36_RS14950 Protein ID WP_135455612.1
Coordinates 3302882..3303208 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OCV36_RS14955 Protein ID WP_135455613.1
Coordinates 3303195..3303509 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV36_RS14930 3298556..3301126 + 2571 WP_135455607.1 tyrosine-type recombinase/integrase -
OCV36_RS14935 3301134..3301469 + 336 WP_135455609.1 hypothetical protein -
OCV36_RS14940 3301466..3302695 + 1230 WP_135455610.1 hypothetical protein -
OCV36_RS14945 3302722..3302853 - 132 WP_261887525.1 hypothetical protein -
OCV36_RS14950 3302882..3303208 + 327 WP_135455612.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCV36_RS14955 3303195..3303509 + 315 WP_135455613.1 DNA-binding transcriptional regulator Antitoxin
OCV36_RS14960 3303930..3305291 + 1362 WP_167853017.1 HipA domain-containing protein -
OCV36_RS14965 3305276..3305764 + 489 WP_135455618.1 helix-turn-helix transcriptional regulator -
OCV36_RS14970 3306186..3307349 + 1164 WP_135455620.1 DUF3596 domain-containing protein -
OCV36_RS14975 3307346..3308056 + 711 WP_245300914.1 hypothetical protein -
OCV36_RS14980 3308160..3308405 + 246 WP_135455622.1 type II toxin-antitoxin system CcdA family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(4-102)

Antitoxin

Antitoxin MqsA/HigA-2

(29-101)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12749.58 Da        Isoelectric Point: 9.9708

>T40320 WP_135455612.1 NZ_AP025483:3302882-3303208 [Vibrio echinoideorum]
MKSIFVESTIFEKYRNEYLSDDEFRLFQAELMSNPKQGDVIQGTGGLRKIRVASKGKRGGSRIIYYFLDEKRRFYLLTIY
GKNEMSDLTADQKKQLKAFMEAWRNEQS

Download         Length: 327 bp

>T40320 NZ_AP025483:3302882-3303208 [Vibrio echinoideorum]
ATGAAAAGTATATTTGTCGAATCAACCATATTTGAAAAGTATCGTAATGAATATCTAAGTGATGATGAGTTTAGGCTTTT
TCAAGCTGAGTTAATGTCTAATCCAAAACAGGGGGACGTGATTCAGGGTACAGGTGGTTTGCGAAAGATTCGAGTTGCAA
GTAAGGGCAAGCGTGGCGGGTCTCGTATTATCTATTACTTCCTCGATGAAAAGCGTCGGTTCTACTTACTGACAATTTAT
GGCAAGAATGAAATGTCCGATTTAACCGCAGACCAAAAGAAACAACTAAAGGCTTTTATGGAGGCGTGGCGTAATGAGCA
ATCGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11896.48 Da        Isoelectric Point: 6.9904

>AT40320 WP_135455613.1 NZ_AP025483:3303195-3303509 [Vibrio echinoideorum]
MSNRDLFTELSSALIEAQEYSKGKLTLKTHHVKDIRELDISPDEIVSIREQFNMSRGVFARLLHTSSRTLENWEQGRSAP
NGQAVTLLKLVQRHPETLSHITEL

Download         Length: 315 bp

>AT40320 NZ_AP025483:3303195-3303509 [Vibrio echinoideorum]
ATGAGCAATCGTGATCTATTTACAGAGTTAAGTTCAGCTCTTATTGAGGCTCAAGAGTATTCCAAGGGCAAACTAACTCT
TAAAACTCATCATGTTAAAGATATCCGCGAACTAGATATTTCACCTGATGAAATCGTGAGTATTCGTGAACAGTTTAATA
TGTCGCGTGGTGTGTTTGCGCGTTTGCTGCATACATCATCTCGTACACTAGAAAACTGGGAACAAGGGCGTAGCGCACCA
AATGGACAAGCGGTAACTCTTCTAAAATTGGTTCAGCGTCATCCGGAAACTCTGTCTCACATCACTGAGCTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References