Detailed information of TA system TA040245

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 789647..790199
• Replicon: chromosome
• Accession: NZ_AP025285
• Organism: Leptogranulimonas caecicola strain TOC12

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: OR601_RS03460
• Protein ID: WP_168896240.1
• Coordinates: 789647..789931 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: OR601_RS03465
• Protein ID: WP_136012909.1
• Coordinates: 789918..790199 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OR601_RS03445 (ATTO_06800)	785774..788074	+	2301	WP_265592212.1	primosomal protein N'	-
OR601_RS03450 (ATTO_06810)	788067..789107	-	1041	WP_265592213.1	aldo/keto reductase	-
OR601_RS03455	789229..789534	-	306	WP_265592214.1	helix-turn-helix transcriptional regulator	-
OR601_RS03460 (ATTO_06820)	789647..789931	-	285	WP_168896240.1	Txe/YoeB family addiction module toxin	Toxin
OR601_RS03465 (ATTO_06830)	789918..790199	-	282	WP_136012909.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
OR601_RS03470 (ATTO_06840)	790386..790979	+	594	WP_136012908.1	recombinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (15-94)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11162.62 Da
• Isoelectric Point: 9.4822

>T40245 WP_168896240.1 NZ_AP025285:c789931-789647 [Leptogranulimonas caecicola]
MSVNRSSQKGRHKVWTTDSWEDYLSWQAGDKATLRRINRLVEEICRTPFEGIGKPEPLKGDLSGLWSRRIDHKNRLVYKP
EDDYVLFLSLRDHY

Nucleotide

• Length: 285 bp

>T40245 NZ_AP025285:c789931-789647 [Leptogranulimonas caecicola]
ATGTCTGTGAATAGGAGTAGTCAGAAAGGACGCCACAAAGTTTGGACGACTGATTCTTGGGAAGATTATCTTTCTTGGCA
AGCAGGTGATAAAGCCACATTGCGAAGAATTAATCGATTAGTAGAAGAAATATGTCGAACTCCTTTCGAAGGCATAGGAA
AACCGGAGCCACTAAAAGGAGACTTATCGGGCTTGTGGTCTAGGCGAATTGATCATAAAAACCGTCTGGTGTATAAGCCT
GAGGATGATTACGTGCTTTTCCTCTCTTTACGCGACCATTATTAG

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10535.79 Da
• Isoelectric Point: 4.1096

>AT40245 WP_136012909.1 NZ_AP025285:c790199-789918 [Leptogranulimonas caecicola]
MECVSYSGFRRNLREYLDKTRDDACEILVTSQDPTSNVVVMNASEYDSLMETLRIYENPELHQKILKGVASAASGDVFIH
DLIDDMDISNVCE

Nucleotide

• Length: 282 bp

>AT40245 NZ_AP025285:c790199-789918 [Leptogranulimonas caecicola]
ATGGAATGTGTAAGCTACTCAGGGTTTCGACGCAATTTGCGGGAATACCTTGATAAGACTCGTGATGATGCCTGCGAGAT
ACTCGTCACGAGCCAAGATCCGACTTCAAATGTCGTAGTAATGAATGCTTCTGAATACGACTCCCTCATGGAAACGTTAA
GAATCTACGAGAATCCAGAGCTTCATCAGAAAATACTCAAAGGAGTAGCCTCGGCTGCATCAGGAGATGTATTTATTCAT
GACTTAATTGATGATATGGATATCTCAAATGTCTGTGAATAG