Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 2358928..2359622 Replicon chromosome
Accession NZ_AP025281
Organism Aliamphritea hakodatensis strain PT3

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag PCI15_RS10810 Protein ID WP_271274346.1
Coordinates 2359227..2359622 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag PCI15_RS10805 Protein ID WP_271274345.1
Coordinates 2358928..2359227 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCI15_RS10780 2354184..2354966 + 783 WP_271274340.1 serine O-acetyltransferase -
PCI15_RS10785 2354971..2355873 + 903 WP_271274341.1 VOC family protein -
PCI15_RS10790 2355901..2357067 + 1167 WP_271274342.1 M20 aminoacylase family protein -
PCI15_RS10795 2357095..2358018 + 924 WP_271274343.1 LysR family transcriptional regulator -
PCI15_RS10800 2358079..2358690 + 612 WP_271274344.1 LysE family translocator -
PCI15_RS10805 2358928..2359227 + 300 WP_271274345.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
PCI15_RS10810 2359227..2359622 + 396 WP_271274346.1 type II toxin-antitoxin system YafO family toxin Toxin
PCI15_RS10815 2359824..2360525 + 702 WP_271274347.1 MOSC domain-containing protein -
PCI15_RS10820 2360540..2361427 + 888 WP_271274348.1 LysR family transcriptional regulator -
PCI15_RS10825 2361563..2362492 + 930 WP_271274349.1 AEC family transporter -
PCI15_RS10830 2362660..2363349 + 690 WP_271274350.1 hypothetical protein -
PCI15_RS10835 2363396..2364322 - 927 WP_271274351.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 15155.24 Da        Isoelectric Point: 6.8384

>T40239 WP_271274346.1 NZ_AP025281:2359227-2359622 [Aliamphritea hakodatensis]
MRIFKGRVLRAQLTEQEQIALTNDFRRYKTTGELPDTFGRDAAYDHPNTPPLIQAGQVQHIHLLDESDQWDVHTIQFYRT
SDKHLVYCPGALHDDCFLLMAILSPDAHAQAKDSNIMRKLGLMAEKFRNIY

Download         Length: 396 bp

>T40239 NZ_AP025281:2359227-2359622 [Aliamphritea hakodatensis]
ATGCGTATTTTCAAAGGACGAGTGCTTCGGGCACAGCTCACGGAACAAGAGCAAATTGCGTTAACCAATGACTTCAGACG
CTATAAAACCACAGGCGAACTGCCCGATACATTTGGCAGAGATGCAGCATACGACCATCCGAATACTCCGCCACTGATAC
AGGCCGGGCAGGTTCAGCATATACATTTGTTGGATGAATCAGATCAGTGGGATGTACATACCATTCAGTTTTACCGAACC
AGTGATAAACACCTGGTGTATTGCCCGGGGGCTTTACATGATGATTGCTTTTTACTGATGGCGATACTGTCACCGGATGC
CCATGCGCAGGCAAAAGACTCCAATATTATGAGAAAACTGGGGCTGATGGCTGAGAAATTCAGAAATATCTATTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10790.06 Da        Isoelectric Point: 4.2597

>AT40239 WP_271274345.1 NZ_AP025281:2358928-2359227 [Aliamphritea hakodatensis]
MSTQAIYAEQTVSITEVRKNPAKYFTEQPVAVLSNNKPAGYMVSAETFEMLIKAVEAQQAPTEFRASFRPTAARLDAIAA
AGREALETASDDELGEFTE

Download         Length: 300 bp

>AT40239 NZ_AP025281:2358928-2359227 [Aliamphritea hakodatensis]
ATGAGTACTCAGGCGATCTACGCGGAACAAACAGTCAGTATTACTGAAGTGCGTAAAAATCCTGCAAAATATTTCACCGA
GCAGCCGGTAGCCGTGTTGTCGAACAACAAGCCTGCCGGTTACATGGTCAGCGCTGAAACATTCGAAATGCTGATTAAAG
CAGTTGAGGCACAGCAGGCACCGACAGAATTCAGGGCGAGCTTCCGGCCAACAGCGGCCCGGCTTGATGCTATCGCAGCG
GCAGGCAGGGAAGCATTGGAAACTGCCTCTGATGATGAACTGGGTGAATTCACTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References