Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2184861..2185078 Replicon chromosome
Accession NZ_AP025177
Organism Staphylococcus aureus strain TPS6281

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag CC22TP_RS10840 Protein ID WP_075583739.1
Coordinates 2184974..2185078 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2184861..2184916 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CC22TP_RS10815 2180917..2181582 - 666 WP_001024097.1 SDR family oxidoreductase -
CC22TP_RS10820 2181734..2182054 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CC22TP_RS10825 2182056..2183036 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CC22TP_RS10830 2183302..2184393 + 1092 WP_000495680.1 hypothetical protein -
- 2184861..2184916 + 56 - - Antitoxin
CC22TP_RS10840 2184974..2185078 - 105 WP_075583739.1 hypothetical protein Toxin
CC22TP_RS10845 2185176..2185337 - 162 Protein_2098 helix-turn-helix domain-containing protein -
CC22TP_RS10850 2185755..2185913 + 159 WP_024928151.1 hypothetical protein -
CC22TP_RS10855 2186573..2187430 - 858 WP_000370944.1 HAD family hydrolase -
CC22TP_RS10860 2187498..2188280 - 783 WP_217654596.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T40012 WP_075583739.1 NZ_AP025177:c2185078-2184974 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

>T40012 NZ_AP025177:c2185078-2184974 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTAATCAAGGCCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT40012 NZ_AP025177:2184861-2184916 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References