Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2228158..2228356 Replicon chromosome
Accession NZ_AP025176
Organism Staphylococcus aureus strain TPS5614

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag LPC25_RS11105 Protein ID WP_075583739.1
Coordinates 2228252..2228356 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2228158..2228196 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPC25_RS11080 2224261..2224926 - 666 WP_001024097.1 SDR family oxidoreductase -
LPC25_RS11085 2225078..2225398 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LPC25_RS11090 2225400..2226380 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
LPC25_RS11095 2226646..2227737 + 1092 WP_000495680.1 hypothetical protein -
LPC25_RS11100 2228138..2228212 + 75 Protein_2152 hypothetical protein -
- 2228158..2228196 + 39 - - Antitoxin
LPC25_RS11105 2228252..2228356 - 105 WP_075583739.1 hypothetical protein Toxin
LPC25_RS11110 2228454..2228615 - 162 Protein_2154 helix-turn-helix domain-containing protein -
LPC25_RS11115 2229033..2229191 + 159 WP_024928151.1 hypothetical protein -
LPC25_RS11120 2229851..2230708 - 858 WP_000370944.1 HAD family hydrolase -
LPC25_RS11125 2230776..2231558 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T39998 WP_075583739.1 NZ_AP025176:c2228356-2228252 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

>T39998 NZ_AP025176:c2228356-2228252 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTAATCAAGGCCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT39998 NZ_AP025176:2228158-2228196 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References