Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 100673..102029 Replicon chromosome
Accession NZ_AP024904
Organism Vibrio rhizosphaerae strain LMG 23790

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag OCV37_RS15660 Protein ID WP_038180120.1
Coordinates 100673..101719 (-) Length 349 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag OCV37_RS15665 Protein ID WP_038180122.1
Coordinates 101703..102029 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV37_RS15635 96073..96408 - 336 WP_038181630.1 helix-turn-helix transcriptional regulator -
OCV37_RS15640 96802..97296 - 495 WP_038181627.1 GNAT family N-acetyltransferase -
OCV37_RS15645 97293..97565 - 273 WP_038181625.1 DUF1778 domain-containing protein -
OCV37_RS15650 98219..99097 + 879 WP_261888159.1 HEPN domain-containing protein -
OCV37_RS15655 99729..100442 - 714 WP_038180117.1 class I SAM-dependent methyltransferase -
OCV37_RS15660 100673..101719 - 1047 WP_038180120.1 HipA domain-containing protein Toxin
OCV37_RS15665 101703..102029 - 327 WP_038180122.1 HipA N-terminal domain-containing protein Antitoxin
OCV37_RS15670 102014..102334 - 321 WP_038180123.1 helix-turn-helix transcriptional regulator -
OCV37_RS15675 102657..103316 - 660 WP_038180125.1 lactate utilization protein -
OCV37_RS15680 103313..104758 - 1446 WP_038180127.1 LutB/LldF family L-lactate oxidation iron-sulfur protein -
OCV37_RS15685 104755..105543 - 789 WP_038180129.1 (Fe-S)-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(60-309)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 349 a.a.        Molecular weight: 39635.22 Da        Isoelectric Point: 5.8539

>T39822 WP_038180120.1 NZ_AP024904:c101719-100673 [Vibrio rhizosphaerae]
MYPSNRSLISLDELNEQNREQVEYKKGEIKTLLGSNRFQIQLPFSRAEFVNELPKKQKGMSISGYQPKLSLAINEDNQLG
VVADKALFILKPSPEEFPHLAENEHATMLVMKFLGFDTPPFGLVRFHDQNEAGELAFIIRRYDRLKAGEEAIHQEQLDAA
MDVRDKYGKTKGDTERYVSYEQACKFLMNKVDSSLNFKKELFNRILVAYFLGNNDLHLRNMGVLLPEQEAIRLAPIYDYV
SIAPYPGYIANENPLALPLLASEEGDNGNTSGYQSHCTYTGYDFLIFAQNIGLNPKLATKMIKDLCAKQDAILDIYRHSF
MPQEHVEKIAEWISSRINYLGQLGHVAV

Download         Length: 1047 bp

>T39822 NZ_AP024904:c101719-100673 [Vibrio rhizosphaerae]
ATGTATCCGAGCAATAGAAGCCTTATTAGCCTCGATGAGCTCAATGAACAAAATAGAGAACAAGTCGAGTACAAAAAAGG
GGAAATCAAAACCCTACTAGGTTCGAATAGATTCCAGATTCAATTACCTTTTTCGCGTGCTGAGTTTGTTAATGAGTTGC
CAAAGAAACAAAAAGGCATGAGTATTTCCGGTTATCAGCCAAAGCTTTCTCTTGCGATCAATGAAGATAATCAGCTAGGG
GTAGTAGCGGATAAAGCGCTATTTATTCTCAAGCCCTCACCAGAAGAATTTCCTCATCTTGCCGAAAACGAGCACGCGAC
AATGTTAGTCATGAAATTCCTCGGTTTCGACACTCCTCCATTTGGATTAGTTCGATTTCATGATCAGAATGAAGCAGGTG
AACTCGCATTTATTATTAGGCGCTATGACCGCTTAAAAGCAGGTGAAGAAGCGATTCATCAAGAGCAATTGGATGCCGCA
ATGGACGTGCGTGACAAGTACGGGAAGACAAAAGGCGATACTGAGAGATACGTTAGCTACGAGCAAGCCTGTAAGTTCTT
AATGAATAAAGTAGACAGCAGCTTAAACTTTAAGAAAGAGTTATTTAACCGAATACTCGTAGCCTACTTTCTCGGGAATA
ATGACCTGCACCTTAGAAATATGGGTGTGCTGCTACCGGAACAAGAGGCCATTCGGCTAGCGCCAATCTATGATTACGTA
TCTATAGCACCTTATCCAGGCTACATCGCAAACGAGAACCCATTAGCATTACCTCTGCTCGCTAGTGAAGAAGGCGATAA
TGGCAATACCAGTGGCTATCAGTCACATTGTACCTACACCGGCTATGACTTTCTCATCTTCGCACAAAATATTGGCCTCA
ACCCTAAGCTGGCGACCAAAATGATTAAAGATTTGTGTGCCAAGCAAGATGCCATTCTTGATATCTACCGTCATAGTTTT
ATGCCGCAAGAACACGTAGAGAAAATAGCTGAATGGATATCGAGCCGAATTAACTATTTGGGTCAATTAGGCCATGTTGC
TGTTTAA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12308.09 Da        Isoelectric Point: 5.7302

>AT39822 WP_038180122.1 NZ_AP024904:c102029-101703 [Vibrio rhizosphaerae]
MDRKVKVLLYGKFCGVLSQNEQGFTFEYEPSYKGRSLSLSMPLEDGPFESKALHPFFQSLAPEGWLKKRYSELQKIDEND
PLGMLLSNGKNLLGAVQLLRLEDHVSEQ

Download         Length: 327 bp

>AT39822 NZ_AP024904:c102029-101703 [Vibrio rhizosphaerae]
ATGGATCGAAAAGTAAAAGTTCTTTTGTACGGAAAGTTTTGCGGTGTTTTGTCTCAAAATGAACAAGGCTTTACATTCGA
ATACGAACCTAGCTACAAAGGTCGTAGCTTATCGCTGAGTATGCCCCTAGAAGATGGGCCATTTGAGAGTAAAGCGCTAC
ACCCTTTTTTCCAGAGTCTTGCACCCGAAGGATGGCTGAAGAAGCGCTACTCAGAACTACAAAAAATTGATGAGAACGAT
CCGCTAGGTATGCTTTTGTCCAACGGCAAAAATTTACTTGGTGCTGTCCAACTGTTGAGATTAGAAGACCATGTATCCGA
GCAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References