Detailed information of TA system TA039820

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/RelE-MqsA
• Location: 44277..44910
• Replicon: chromosome
• Accession: NZ_AP024904
• Organism: Vibrio rhizosphaerae strain LMG 23790

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: OCV37_RS15430
• Protein ID: WP_038184415.1
• Coordinates: 44277..44609 (+)
• Length: 111 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: OCV37_RS15435
• Protein ID: WP_038184412.1
• Coordinates: 44596..44910 (+)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCV37_RS15415	40074..41990	-	1917	WP_038184423.1	methyl-accepting chemotaxis protein	-
OCV37_RS15420	42305..43105	+	801	WP_038184421.1	class III extradiol ring-cleavage dioxygenase	-
OCV37_RS15425	43208..43897	+	690	WP_245609147.1	alpha/beta hydrolase	-
OCV37_RS15430	44277..44609	+	333	WP_038184415.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCV37_RS15435	44596..44910	+	315	WP_038184412.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
OCV37_RS15440	45350..47491	+	2142	WP_157635065.1	TonB-dependent receptor	-
OCV37_RS15445	47670..48575	+	906	WP_157635070.1	Fe(3+) dicitrate ABC transporter substrate-binding protein	-
OCV37_RS15450	48620..49603	+	984	WP_038184408.1	iron chelate uptake ABC transporter family permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (4-104)

Antitoxin

• Cro/C1-type helix-turn-helix domain (43-92)

Sequences

Toxin

Protein

• Length: 111 a.a.
• Molecular weight: 13035.02 Da
• Isoelectric Point: 10.2254

>T39820 WP_038184415.1 NZ_AP024904:44277-44609 [Vibrio rhizosphaerae]
MKSIFIESTIFEKYRSEYLSDEAFRLFQAELMLNPKRGDVIQGTGGLRKIRVVSKGKGKQGGSRVIYYFFDEKRRFYLLT
IYSKHEMSDLTTDQKKQLKAFMEAWRNEQS

Nucleotide

• Length: 333 bp

>T39820 NZ_AP024904:44277-44609 [Vibrio rhizosphaerae]
ATGAAAAGTATATTTATCGAATCGACCATCTTTGAAAAGTACCGCAGTGAATACCTTAGTGATGAAGCGTTTAGACTTTT
CCAAGCGGAGCTGATGTTAAACCCTAAGCGGGGAGACGTCATTCAAGGTACTGGTGGATTGAGAAAGATTCGGGTGGTAA
GTAAAGGCAAGGGGAAACAGGGTGGTTCTCGCGTGATCTATTACTTCTTCGATGAAAAACGACGTTTTTACTTGCTCACC
ATTTACAGCAAGCATGAAATGTCAGACTTAACCACAGACCAAAAGAAACAATTGAAGGCTTTTATGGAGGCGTGGCGTAA
TGAGCAATCGTGA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 11644.29 Da
• Isoelectric Point: 8.8401

>AT39820 WP_038184412.1 NZ_AP024904:44596-44910 [Vibrio rhizosphaerae]
MSNRDLFAELSSALVEAKDHSNGKITLKKHKVNDVSELSLSPDEIVSIREQFNMSRGIFARLLHTSSRTLESWEQGRSVP
NGQAITLLKLVQRHPEILSHIAAL

Nucleotide

• Length: 315 bp

>AT39820 NZ_AP024904:44596-44910 [Vibrio rhizosphaerae]
ATGAGCAATCGTGACTTATTTGCAGAATTAAGTTCAGCGCTTGTCGAGGCTAAAGACCATTCGAATGGCAAGATTACACT
AAAAAAACATAAAGTGAATGACGTGAGTGAGTTAAGTCTTTCACCTGATGAAATCGTGAGTATTCGCGAACAGTTTAATA
TGTCTCGCGGTATATTTGCGCGTTTACTACACACATCATCTCGTACGTTAGAAAGCTGGGAGCAAGGGCGCAGCGTACCA
AATGGGCAAGCGATCACTCTCCTGAAACTGGTTCAGCGTCATCCGGAGATCTTGTCGCATATTGCAGCGTTATAA