Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 2837420..2838120 Replicon chromosome
Accession NZ_AP024895
Organism Vibrio porteresiae DSM 19223 strain MSSRF30

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag OCV11_RS12910 Protein ID WP_261893303.1
Coordinates 2837420..2837830 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag OCV11_RS12915 Protein ID WP_261893304.1
Coordinates 2837827..2838120 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV11_RS12890 2833300..2835111 + 1812 WP_261893299.1 branched-chain amino acid ABC transporter ATP-binding protein/permease -
OCV11_RS12895 2835108..2835881 + 774 WP_261893300.1 ABC transporter ATP-binding protein -
OCV11_RS12900 2835956..2836723 + 768 WP_261893301.1 class II aldolase/adducin family protein -
OCV11_RS12905 2836874..2837353 + 480 WP_261893302.1 MarR family winged helix-turn-helix transcriptional regulator -
OCV11_RS12910 2837420..2837830 - 411 WP_261893303.1 type II toxin-antitoxin system YafO family toxin Toxin
OCV11_RS12915 2837827..2838120 - 294 WP_261893304.1 hypothetical protein Antitoxin
OCV11_RS12920 2838329..2838667 + 339 WP_261893305.1 cytosolic protein -
OCV11_RS12925 2838834..2839607 - 774 WP_261893306.1 transporter substrate-binding domain-containing protein -
OCV11_RS12930 2839636..2840439 - 804 WP_261893307.1 carbon-nitrogen hydrolase family protein -
OCV11_RS12935 2840451..2841617 - 1167 WP_261893308.1 methionine aminotransferase -
OCV11_RS12940 2841746..2842624 + 879 WP_261893309.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(32-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15737.97 Da        Isoelectric Point: 7.9780

>T39806 WP_261893303.1 NZ_AP024895:c2837830-2837420 [Vibrio porteresiae DSM 19223]
VSNSLNIRVFKHKILIDSLTESELQSLAKDFKHYKETGQKPDFFGRDEAYDHPNTLPLLKSEEVKHIHLAASDAPFLSSI
QFYQTSDKHLVYCQGWNDRSCFLLIAILAPNAHEQARNRIIMHNLGLIAEKFRQKF

Download         Length: 411 bp

>T39806 NZ_AP024895:c2837830-2837420 [Vibrio porteresiae DSM 19223]
GTGAGTAACTCGTTAAATATTCGAGTTTTTAAGCATAAGATCTTAATTGACTCACTGACGGAAAGTGAGCTTCAATCGTT
GGCTAAAGACTTTAAACACTACAAGGAAACGGGGCAAAAACCGGATTTTTTTGGTCGAGATGAAGCTTATGATCATCCCA
ACACATTACCGCTCTTGAAATCAGAGGAAGTGAAGCACATTCATTTAGCTGCTAGTGATGCTCCGTTCTTAAGTTCTATT
CAGTTTTACCAAACGAGTGATAAGCACCTAGTATATTGTCAAGGTTGGAATGATCGTAGTTGCTTTCTGTTAATCGCCAT
CCTTGCTCCTAACGCTCATGAGCAAGCTCGTAATCGAATTATCATGCATAACTTGGGTTTGATAGCCGAAAAATTTAGGC
AGAAATTCTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10691.06 Da        Isoelectric Point: 4.6631

>AT39806 WP_261893304.1 NZ_AP024895:c2838120-2837827 [Vibrio porteresiae DSM 19223]
MKTSRIYAEKAVSSSEARKHFKDCLSGEPVVILSNNEPAGYMMSATFFEGLMKALEAKNSGSVSSFRPMSARLEVIAHLN
AQALTELEESDLDDFQE

Download         Length: 294 bp

>AT39806 NZ_AP024895:c2838120-2837827 [Vibrio porteresiae DSM 19223]
ATGAAAACAAGTCGAATCTATGCAGAAAAAGCTGTGTCATCAAGCGAAGCTAGAAAGCATTTTAAAGATTGCTTATCAGG
AGAGCCTGTCGTAATCCTATCGAACAATGAGCCAGCGGGTTATATGATGAGCGCTACTTTTTTTGAAGGACTAATGAAAG
CTTTAGAAGCTAAGAATTCTGGCTCTGTTTCATCATTTAGGCCAATGAGTGCTCGCCTAGAAGTCATTGCTCATCTGAAT
GCTCAAGCATTAACCGAGCTCGAAGAAAGTGATTTGGATGATTTTCAAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References