Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 833375..834075 Replicon chromosome
Accession NZ_AP024871
Organism Vibrio gallicus strain CIP 107863

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag OCU28_RS03940 Protein ID WP_261817036.1
Coordinates 833665..834075 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag OCU28_RS03935 Protein ID WP_261817035.1
Coordinates 833375..833668 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU28_RS03900 828841..829335 + 495 WP_261817030.1 YbaY family lipoprotein -
OCU28_RS03905 829410..829712 - 303 WP_261817031.1 MGMT family protein -
OCU28_RS03910 829772..830506 + 735 WP_261817032.1 hypothetical protein -
OCU28_RS03920 830933..832030 - 1098 WP_261817033.1 transposase -
OCU28_RS03925 831921..832457 + 537 Protein_744 DUF1214 domain-containing protein -
OCU28_RS03930 832629..832967 - 339 WP_261817034.1 cytosolic protein -
OCU28_RS03935 833375..833668 + 294 WP_261817035.1 hypothetical protein Antitoxin
OCU28_RS03940 833665..834075 + 411 WP_261817036.1 type II toxin-antitoxin system YafO family toxin Toxin
OCU28_RS03945 834354..835634 + 1281 WP_261817037.1 hypothetical protein -
OCU28_RS03950 836092..836982 + 891 WP_261817038.1 AraC family transcriptional regulator -
OCU28_RS03955 837153..837827 + 675 WP_261817039.1 fibrobacter succinogenes major paralogous domain-containing protein -
OCU28_RS03960 837935..838867 + 933 WP_261817040.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(33-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15840.16 Da        Isoelectric Point: 7.9568

>T39781 WP_261817036.1 NZ_AP024871:833665-834075 [Vibrio gallicus]
VSKSLNIRIFKHKILIDSLTKSELQSLTKDFRYYKETGQKPEFFGRDEAYDHPNTLPILKSEEVKHIHLAAMDAPFLSSI
QFYQTSDKHLVYCQGWSDPSCFLLIAILAPDAHEQTRNRTIMHNLGLIAEKFRQQF

Download         Length: 411 bp

>T39781 NZ_AP024871:833665-834075 [Vibrio gallicus]
GTGAGTAAGTCACTAAATATTAGAATTTTTAAGCATAAGATTTTAATTGATTCACTTACTAAAAGTGAGCTTCAATCTTT
GACTAAGGACTTTAGATATTACAAAGAGACTGGTCAAAAACCAGAATTTTTTGGTCGTGATGAAGCCTATGATCACCCTA
ATACATTGCCAATTCTAAAATCAGAAGAAGTGAAGCACATTCATTTAGCAGCTATGGATGCTCCGTTTCTCAGCTCTATC
CAATTCTACCAAACGAGTGATAAGCATTTAGTCTATTGCCAAGGCTGGAGTGATCCTAGTTGTTTTTTGTTAATCGCTAT
CCTTGCACCAGATGCTCATGAACAAACTCGAAATAGAACTATCATGCATAATTTAGGTTTGATAGCTGAAAAGTTTCGGC
AGCAATTTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10599.01 Da        Isoelectric Point: 4.8377

>AT39781 WP_261817035.1 NZ_AP024871:833375-833668 [Vibrio gallicus]
MKTSTIYAEKAVSSSEARKHFKDCLSGEPVVVLSNNEPAGYMMSATFFEGLMKALEGKNADSVSSFRPMSARLEVIAHLN
AHALTELDESILGEFQE

Download         Length: 294 bp

>AT39781 NZ_AP024871:833375-833668 [Vibrio gallicus]
ATGAAAACAAGTACAATCTATGCTGAAAAAGCAGTGTCATCAAGCGAAGCTAGAAAGCATTTTAAAGATTGCTTATCAGG
GGAGCCAGTTGTCGTTTTATCAAATAACGAGCCTGCTGGTTATATGATGAGCGCCACTTTTTTTGAAGGACTTATGAAAG
CTTTAGAAGGCAAAAATGCTGACTCTGTTTCATCATTTAGGCCAATGAGTGCTCGCTTAGAAGTCATTGCCCATCTTAAT
GCTCATGCATTAACAGAGCTTGATGAGAGTATCTTGGGTGAGTTTCAAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References