Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2543843..2544027 Replicon chromosome
Accession NZ_AP024742
Organism Staphylococcus aureus strain 59736

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OCX51_RS12810 Protein ID WP_000482647.1
Coordinates 2543920..2544027 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2543843..2543903 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX51_RS12795 2539317..2539484 - 168 WP_001790576.1 hypothetical protein -
OCX51_RS12800 2539715..2541448 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OCX51_RS12805 2541473..2543236 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2543843..2543903 + 61 - - Antitoxin
OCX51_RS12810 2543920..2544027 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
OCX51_RS12815 2544161..2544547 - 387 WP_000779360.1 flippase GtxA -
OCX51_RS12820 2544805..2545947 + 1143 WP_001176871.1 glycerate kinase -
OCX51_RS12825 2546007..2546666 + 660 WP_000831301.1 membrane protein -
OCX51_RS12830 2546848..2548059 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OCX51_RS12835 2548182..2548655 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T39419 WP_000482647.1 NZ_AP024742:c2544027-2543920 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T39419 NZ_AP024742:c2544027-2543920 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT39419 NZ_AP024742:2543843-2543903 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References