Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2265548..2265745 Replicon chromosome
Accession NZ_AP024742
Organism Staphylococcus aureus strain 59736

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OCX51_RS11350 Protein ID WP_001802298.1
Coordinates 2265641..2265745 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2265548..2265586 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX51_RS11325 2261789..2262454 - 666 WP_001024095.1 SDR family oxidoreductase -
OCX51_RS11330 2262606..2262926 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OCX51_RS11335 2262928..2263908 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
OCX51_RS11340 2264174..2265265 + 1092 WP_000495683.1 hypothetical protein -
OCX51_RS11345 2265528..2265602 + 75 Protein_2195 hypothetical protein -
- 2265548..2265586 + 39 - - Antitoxin
OCX51_RS11350 2265641..2265745 - 105 WP_001802298.1 hypothetical protein Toxin
OCX51_RS11355 2266262..2266432 + 171 WP_001792292.1 transposase -
OCX51_RS11360 2266425..2266583 + 159 WP_001792784.1 hypothetical protein -
OCX51_RS11365 2267242..2268099 - 858 WP_000370917.1 HAD family hydrolase -
OCX51_RS11370 2268167..2268949 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T39417 WP_001802298.1 NZ_AP024742:c2265745-2265641 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T39417 NZ_AP024742:c2265745-2265641 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT39417 NZ_AP024742:2265548-2265586 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References