Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2540090..2540274 Replicon chromosome
Accession NZ_AP024738
Organism Staphylococcus aureus strain 59731

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OCX20_RS12785 Protein ID WP_000482647.1
Coordinates 2540167..2540274 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2540090..2540150 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX20_RS12770 2535564..2535731 - 168 WP_001790576.1 hypothetical protein -
OCX20_RS12775 2535962..2537695 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OCX20_RS12780 2537720..2539483 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2540090..2540150 + 61 - - Antitoxin
OCX20_RS12785 2540167..2540274 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
OCX20_RS12790 2540408..2540794 - 387 WP_000779360.1 flippase GtxA -
OCX20_RS12795 2541052..2542194 + 1143 WP_001176871.1 glycerate kinase -
OCX20_RS12800 2542254..2542913 + 660 WP_000831301.1 membrane protein -
OCX20_RS12805 2543095..2544306 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OCX20_RS12810 2544429..2544902 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T39399 WP_000482647.1 NZ_AP024738:c2540274-2540167 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T39399 NZ_AP024738:c2540274-2540167 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT39399 NZ_AP024738:2540090-2540150 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References